PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1993549-6	1991	GM-CSF mRNA was, however, detected in the tumor cells in the presence of an mRNA-stabilizing agent, cycloheximide, suggesting the possibility that the tumor cells of this type were transcribing GM-CSF gene, and secreting it in undetectable levels; (3) in culture of the 4 remaining poorly or non-metastatic tumors, neither CSF activity nor GM-CSF mRNA could be detected even in the presence of cycloheximide.	Cycloheximide	100-113	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	0-6	
9880508-12	1999	Northern analysis demonstrates that cycloheximide treatment abrogates the capacity of GM-CSF to decrease beta5 mRNA levels.	Cycloheximide	36-49	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	86-92	
7930569-4	1994	However, comparative studies using extracts of D10.G4.1 cells treated with the cellular activators Con A and PMA and the inhibitors cycloheximide and cyclosporin A indicated that the binding activities to the conserved elements in the IL-5 and GM-CSF genes (designated NF-IL-5A and NF-GM-CSFA, respectively) are regulated by different signaling pathways.	Cycloheximide	132-145	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	244-250	
7577656-9	1995	Cycloheximide (CHX) incubation abolished the inhibitory effect of IFN-alpha on GM-CSF expression, suggesting the requirement of a labile protein.	Cycloheximide	0-13	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	79-85	
7577656-9	1995	Cycloheximide (CHX) incubation abolished the inhibitory effect of IFN-alpha on GM-CSF expression, suggesting the requirement of a labile protein.	Cycloheximide	15-18	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	79-85	
1535090-10	1992	The protein synthesis inhibitor cycloheximide abrogated GM-CSF receptor up-regulation induced by both rMuIL-3 and rMuGM-CSF, whereas actinomycin D inhibited only the second (8-24 h) phase of GM-CSF receptor up-regulation induced by exposure to high concentrations rMuGM-CSF (10 ng/ml).	Cycloheximide	32-45	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	56-62	
1535090-10	1992	The protein synthesis inhibitor cycloheximide abrogated GM-CSF receptor up-regulation induced by both rMuIL-3 and rMuGM-CSF, whereas actinomycin D inhibited only the second (8-24 h) phase of GM-CSF receptor up-regulation induced by exposure to high concentrations rMuGM-CSF (10 ng/ml).	Cycloheximide	32-45	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	117-123	
1993549-6	1991	GM-CSF mRNA was, however, detected in the tumor cells in the presence of an mRNA-stabilizing agent, cycloheximide, suggesting the possibility that the tumor cells of this type were transcribing GM-CSF gene, and secreting it in undetectable levels; (3) in culture of the 4 remaining poorly or non-metastatic tumors, neither CSF activity nor GM-CSF mRNA could be detected even in the presence of cycloheximide.	Cycloheximide	394-407	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	0-6	
3123388-7	1988	CSF production by peritoneal adherent cells was completely inhibited by cycloheximide (50 micrograms/ml), and neither the elimination of T cells from the peritoneal adherent cells by treating them with anti-Thy-1.2 antibody plus complement nor the addition of T cells affected CSF production.	Cycloheximide	72-85	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	0-3	
2824613-14	1987	However, both mediators act by inducing the transcription of the HDC gene and de novo synthesis of this enzyme since actinomycin D or cycloheximide abolish GM-CSF-or IL-3-induced histamine-producing cell-stimulating activity.	Cycloheximide	134-147	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	156-162	
6602193-9	1983	Only 8% secretion was noted at 4 degrees C; however, this increased to 70% to 80% at 37 degrees C. Development of binding sites in vitro appeared to require new protein synthesis, since addition of 1 microgram/ml cycloheximide during the preincubation prevented the subsequent CSF binding.	Cycloheximide	213-226	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	277-280