PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11502362-4 2001 The increase in Isl-1 mRNA levels upon NGF addition was rapid and occurred even in the presence of cycloheximide. Cycloheximide 99-112 nerve growth factor Rattus norvegicus 39-42 10457374-5 1999 In addition, stimulation of NGF but not S-100beta release was substantially reduced in cultures treated with the protein synthesis inhibitor cycloheximide. Cycloheximide 141-154 nerve growth factor Rattus norvegicus 28-31 10781822-5 2000 Treatment of PC12 cells with actinomycin D or cycloheximide completely abolishes the NGF-induced elevation of SM. Cycloheximide 46-59 nerve growth factor Rattus norvegicus 85-88 1708303-8 1991 NGF synthesized by astrocytes is rapidly secreted into the culture medium and aFGF enhances NGF secretion from the transcription level, because cycloheximide and actinomycin-D completely inhibited NGF secretion by astrocytes in the presence or absence of aFGF. Cycloheximide 144-157 nerve growth factor Rattus norvegicus 0-3 9662427-5 1998 The response to NGF was maximal in the presence of cycloheximide, and RA also reduced the superinduction of NGFI-B and c-fos mRNA levels. Cycloheximide 51-64 nerve growth factor Rattus norvegicus 16-19 9349553-2 1997 Here we show that NGF withdrawal induces actinomycin D- and cycloheximide-sensitive caspase (ICE-like) activity. Cycloheximide 60-73 nerve growth factor Rattus norvegicus 18-21 9130244-8 1997 NGF maintained catalase mRNA levels of actinomycin D (ACT-D) treated PC12 cells at twice that of cells exposed to ACT-D alone, delaying the rate of decay for catalase mRNA for 24 h. The NGF induction of GSH-Px and catalase mRNA was inhibited by cycloheximide (CHX) treatment with a slight decrease in their mRNA levels due to prolonged exposure to CHX. Cycloheximide 245-258 nerve growth factor Rattus norvegicus 0-3 9130244-8 1997 NGF maintained catalase mRNA levels of actinomycin D (ACT-D) treated PC12 cells at twice that of cells exposed to ACT-D alone, delaying the rate of decay for catalase mRNA for 24 h. The NGF induction of GSH-Px and catalase mRNA was inhibited by cycloheximide (CHX) treatment with a slight decrease in their mRNA levels due to prolonged exposure to CHX. Cycloheximide 245-258 nerve growth factor Rattus norvegicus 186-189 9130244-8 1997 NGF maintained catalase mRNA levels of actinomycin D (ACT-D) treated PC12 cells at twice that of cells exposed to ACT-D alone, delaying the rate of decay for catalase mRNA for 24 h. The NGF induction of GSH-Px and catalase mRNA was inhibited by cycloheximide (CHX) treatment with a slight decrease in their mRNA levels due to prolonged exposure to CHX. Cycloheximide 260-263 nerve growth factor Rattus norvegicus 0-3 9130244-8 1997 NGF maintained catalase mRNA levels of actinomycin D (ACT-D) treated PC12 cells at twice that of cells exposed to ACT-D alone, delaying the rate of decay for catalase mRNA for 24 h. The NGF induction of GSH-Px and catalase mRNA was inhibited by cycloheximide (CHX) treatment with a slight decrease in their mRNA levels due to prolonged exposure to CHX. Cycloheximide 260-263 nerve growth factor Rattus norvegicus 186-189 7757262-9 1995 However, chronic addition of cycloheximide prior to deprivation greatly impaired the differentiation of NGF/dbcAMP cells, allowing these cells to withstand trophic support withdrawal. Cycloheximide 29-42 nerve growth factor Rattus norvegicus 104-107 7901332-7 1993 Treatment with NGF and cycloheximide, or actinomycin D, which inhibit protein and RNA synthesis, respectively, blocked the NGF stimulation of GCS and glucose 6-phosphate dehydrogenase. Cycloheximide 23-36 nerve growth factor Rattus norvegicus 123-126 1279189-3 1992 p75NGFR mRNA levels are increased by either cycloheximide or nerve growth factor (NGF) treatment of C6 cells as measured using RT-PCR. Cycloheximide 44-57 nerve growth factor Rattus norvegicus 3-6 1875907-11 1991 Treatment of astrocytes with cycloheximide increased (about 6-fold) NGF mRNA content, and this content failed to increase further with IL-1 or bFGF treatment. Cycloheximide 29-42 nerve growth factor Rattus norvegicus 68-71 9712850-9 1998 Cycloheximide pretreatment abolished the post-transcriptional effect of NGF, indicating that de novo protein synthesis was required for the observed increase in m4 mRNA stability. Cycloheximide 0-13 nerve growth factor Rattus norvegicus 72-75 9038227-7 1997 Incubation of PC12 cells with a transcription inhibitor (actinomycin D) or protein synthesis inhibitors (anisomycin or cycloheximide) attenuated the ability of NGF to decrease sGC subunit mRNA levels. Cycloheximide 119-132 nerve growth factor Rattus norvegicus 160-163 1671048-9 1991 NGF treatment for 6 h increased NGF receptor mRNA fourfold; this increase was inhibited by cycloheximide. Cycloheximide 91-104 nerve growth factor Rattus norvegicus 0-3 1965839-3 1990 The expression of NGF-R mRNA in C6 cells can be up-regulated by cycloheximide and its own ligand, NGF; and it can be rapidly down-regulated by epidermal growth factor (EGF). Cycloheximide 64-77 nerve growth factor Rattus norvegicus 18-21 2542296-2 1989 The c-jun transcripts increase within 15 min after NGF addition, peak at 1 h, and decline to basal level by 4 h. Actinomycin D inhibits the increase, and cycloheximide prevents the decrease of c-jun mRNA. Cycloheximide 154-167 nerve growth factor Rattus norvegicus 51-54 2160601-4 1990 The response to NGF was blocked by cycloheximide, indicating a requirement for ongoing protein synthesis. Cycloheximide 35-48 nerve growth factor Rattus norvegicus 16-19 6470042-6 1984 The NGF production was blocked by inhibitors of messenger RNA synthesis (actinomycin D) and of polyadenylation (9-beta-D-arabinofuranosyladenine) as well as by inhibitors of translation (cycloheximide). Cycloheximide 187-200 nerve growth factor Rattus norvegicus 4-7 2914963-4 1989 The induction of ornithine decarboxylase by both NGF and PMA is inhibited by cycloheximide and actinomycin D suggesting that both agents increase enzyme activity by increasing gene transcription. Cycloheximide 77-90 nerve growth factor Rattus norvegicus 49-52