PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11414630-10 2001 This increase in TF expression and PCA of intact cells incubated with Hb was significantly inhibited by cycloheximide at a concentration of 10 microg/ml (P < 0.01). Cycloheximide 104-117 coagulation factor III, tissue factor Homo sapiens 17-19 16113838-8 2005 However, the induction of TF was abrogated by cycloheximide as well as actinomycin-D, inhibitors or protein- and mRNA-synthesis, respectively, demonstrating that EGF mediates its effect through activation of the TF gene. Cycloheximide 46-59 coagulation factor III, tissue factor Homo sapiens 26-28 16113838-8 2005 However, the induction of TF was abrogated by cycloheximide as well as actinomycin-D, inhibitors or protein- and mRNA-synthesis, respectively, demonstrating that EGF mediates its effect through activation of the TF gene. Cycloheximide 46-59 coagulation factor III, tissue factor Homo sapiens 212-214 11003574-8 2000 LXA(4)-induced TF activity was dose dependent, cycloheximide sensitive, and associated with increased TF mRNA levels. Cycloheximide 47-60 coagulation factor III, tissue factor Homo sapiens 15-17 8218112-7 1993 Cycloheximide inhibited the induction of TF protein activity, but it enhanced the accumulation of TF mRNA in MM-LDL- and LPS-induced endothelial cells. Cycloheximide 0-13 coagulation factor III, tissue factor Homo sapiens 41-43 9851744-5 1998 PBL-induced TF activity was inhibited by cycloheximide or actinomycin D, indicating active protein synthesis that was confirmed by the increase in TF mRNA detected by reverse transcription-polymerase chain reaction. Cycloheximide 41-54 coagulation factor III, tissue factor Homo sapiens 12-14 8054453-5 1994 Since cycloheximide alone also caused an increase of TF mRNA levels and gene transcription it is concluded that the transcriptional activation of the TF gene does not require protein synthesis. Cycloheximide 6-19 coagulation factor III, tissue factor Homo sapiens 53-55 8054453-5 1994 Since cycloheximide alone also caused an increase of TF mRNA levels and gene transcription it is concluded that the transcriptional activation of the TF gene does not require protein synthesis. Cycloheximide 6-19 coagulation factor III, tissue factor Homo sapiens 150-152 7517205-10 1994 The increase in PAI-1 and TF mRNA was also seen when HepG2 were incubated with HGF in the presence of cycloheximide, thereby indicating that de novo protein synthesis is not required to mediate the effect. Cycloheximide 102-115 coagulation factor III, tissue factor Homo sapiens 26-28 8218112-7 1993 Cycloheximide inhibited the induction of TF protein activity, but it enhanced the accumulation of TF mRNA in MM-LDL- and LPS-induced endothelial cells. Cycloheximide 0-13 coagulation factor III, tissue factor Homo sapiens 98-100 8420984-9 1993 Chimeric tissue factor.beta-globin mRNAs were superinduced by the protein synthesis inhibitor cycloheximide, and this superinduction may be due in part to stabilization of the mRNA. Cycloheximide 94-107 coagulation factor III, tissue factor Homo sapiens 9-22 8405069-7 1993 This inhibitory effect of IL-10 was already apparent at the TF mRNA level and was prevented by co-incubation with cycloheximide (20 micrograms/ml). Cycloheximide 114-127 coagulation factor III, tissue factor Homo sapiens 60-62 1985911-1 1991 We have cloned a serum- and cycloheximide-inducible mRNA from AKR-2B murine fibroblasts which encodes a protein with significant sequence similarity to human tissue factor, a cellular initiator of the blood coagulation cascade. Cycloheximide 28-41 coagulation factor III, tissue factor Homo sapiens 158-171 7678000-4 1993 The increase was detectable within 2 h and declined to near basal level by 6 h. Induction of TF mRNA was not blocked by cycloheximide, treatment with cycloheximide alone also increased TF mRNA levels, and thrombin in combination with cycloheximide further enhanced the accumulation of TF mRNA. Cycloheximide 150-163 coagulation factor III, tissue factor Homo sapiens 93-95 7678000-4 1993 The increase was detectable within 2 h and declined to near basal level by 6 h. Induction of TF mRNA was not blocked by cycloheximide, treatment with cycloheximide alone also increased TF mRNA levels, and thrombin in combination with cycloheximide further enhanced the accumulation of TF mRNA. Cycloheximide 150-163 coagulation factor III, tissue factor Homo sapiens 185-187 7678000-4 1993 The increase was detectable within 2 h and declined to near basal level by 6 h. Induction of TF mRNA was not blocked by cycloheximide, treatment with cycloheximide alone also increased TF mRNA levels, and thrombin in combination with cycloheximide further enhanced the accumulation of TF mRNA. Cycloheximide 150-163 coagulation factor III, tissue factor Homo sapiens 185-187 7678000-4 1993 The increase was detectable within 2 h and declined to near basal level by 6 h. Induction of TF mRNA was not blocked by cycloheximide, treatment with cycloheximide alone also increased TF mRNA levels, and thrombin in combination with cycloheximide further enhanced the accumulation of TF mRNA. Cycloheximide 150-163 coagulation factor III, tissue factor Homo sapiens 93-95 7678000-4 1993 The increase was detectable within 2 h and declined to near basal level by 6 h. Induction of TF mRNA was not blocked by cycloheximide, treatment with cycloheximide alone also increased TF mRNA levels, and thrombin in combination with cycloheximide further enhanced the accumulation of TF mRNA. Cycloheximide 150-163 coagulation factor III, tissue factor Homo sapiens 185-187 7678000-4 1993 The increase was detectable within 2 h and declined to near basal level by 6 h. Induction of TF mRNA was not blocked by cycloheximide, treatment with cycloheximide alone also increased TF mRNA levels, and thrombin in combination with cycloheximide further enhanced the accumulation of TF mRNA. Cycloheximide 150-163 coagulation factor III, tissue factor Homo sapiens 185-187 1803619-0 1991 Discordant expression of tissue factor antigen and procoagulant activity on human monocytes activated with LPS and low dose cycloheximide. Cycloheximide 124-137 coagulation factor III, tissue factor Homo sapiens 25-38 1803619-8 1991 These studies indicate that TF cofactor activity on LPS/CHX-treated monocytes was approximately 7 times greater than that present on LPS-treated cells. Cycloheximide 56-59 coagulation factor III, tissue factor Homo sapiens 28-30 1803619-9 1991 Increased TF functional activity may be due to CHX-induced alterations in the type and content of phospholipids (PL) in the cell membrane. Cycloheximide 47-50 coagulation factor III, tissue factor Homo sapiens 10-12 1693617-7 1990 Cycloheximide (10 micrograms/ml) alone caused induction of TF mRNA. Cycloheximide 0-13 coagulation factor III, tissue factor Homo sapiens 59-61 2555368-6 1989 Nuclear runoff assays showed that PMA, TNF, or cycloheximide induced transcription of the tissue factor gene, whereas the genes for thrombomodulin, PAI-1, and PAI-2 apparently were transcribed at the same relative rate in the presence or absence of these agents. Cycloheximide 47-60 coagulation factor III, tissue factor Homo sapiens 90-103 2555368-7 1989 Treatment of cells with cycloheximide stabilized tissue factor and PAI-2 mRNAs and increased their induction by PMA or TNF. Cycloheximide 24-37 coagulation factor III, tissue factor Homo sapiens 49-62 2715194-4 1989 The parallel rise in antigenically positive protein and procoagulant activity was first observed about 2 h after serum stimulation with a peak at 12 h followed by a slow decline during the next 36 h. The serum-induced synthesis of the tissue factor mRNA was independent of de novo protein synthesis as demonstrated by the increased tissue factor mRNA levels generated in the presence of cycloheximide. Cycloheximide 387-400 coagulation factor III, tissue factor Homo sapiens 235-248 2718149-4 1989 Cycloheximide by itself induced the accumulation of high levels of tissue factor mRNA in these cells. Cycloheximide 0-13 coagulation factor III, tissue factor Homo sapiens 67-80