PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10375003-3 1999 Primary mouse embryo fibroblasts and bone marrow cells from Mgmt -/- mice were significantly more sensitive to the toxic effects of the chemotherapeutic alkylating agents 1,3-bis(2-chloroethyl)-1-nitrosourea, streptozotocin and temozolomide than those from Mgmt wild-type mice. Streptozocin 209-223 O-6-methylguanine-DNA methyltransferase Mus musculus 60-64 1537073-7 1992 The activity of O6-methylguanine-DNA methyltransferase in mer+ cells was greatly reduced by treatment with O6-methylguanine or streptozotocin, and the combination of the two drugs led to enzyme levels similar to those observed in mer- cells. Streptozocin 127-141 O-6-methylguanine-DNA methyltransferase Mus musculus 16-54