PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11700114-1 2001 [reaction--see text] The synthesis of oxime-linked mucin mimics was accomplished via the incorporation of multiple ketone residues into a peptide followed by reaction with aminooxy sugars corresponding to the tumor-related T(N) and sialyl T(N) (ST(N)) antigens. Sugars 181-187 LOC100508689 Homo sapiens 51-56 21136536-3 2011 Adsorption of mucin glycoprotein to the polymer brush took place due to boronate/sugar interactions between the glycoprotein and the graft copolymer and resulted in further increase of the brush height by ca. Sugars 81-86 LOC100508689 Homo sapiens 14-19 21244730-5 2010 (4) Mucin glycoprotein MUC7 that has known bactericidal activity displays an overall reduced terminal sugar profile in biofilm positive CRS patients. Sugars 102-107 LOC100508689 Homo sapiens 4-9 20557876-3 2010 Biotinylated mucin was immobilized on streptavidin-coated beads, and the binding specificities of the major mucin sugar chains, as determined by GC-MS and MALDI-ToF, were monitored using fluorescein-labeled lectins. Sugars 114-119 LOC100508689 Homo sapiens 13-18 20557876-3 2010 Biotinylated mucin was immobilized on streptavidin-coated beads, and the binding specificities of the major mucin sugar chains, as determined by GC-MS and MALDI-ToF, were monitored using fluorescein-labeled lectins. Sugars 114-119 LOC100508689 Homo sapiens 108-113 17915910-5 2007 Data from two independent probes, fluorophores conjugated directly to the polymer backbone and fluorescent proteins bound to the sugar groups, unexpectedly show that the mucin mimic molecules lie flat along the membrane. Sugars 129-134 LOC100508689 Homo sapiens 170-175 17255563-8 2007 During stable disease, the vol/vol quantity of MUC5AC protein was 89% less than normal mucus, and the mucin-associated sugars, measured using a lectin binding assay, were 46% less compared with normal mucus. Sugars 119-125 LOC100508689 Homo sapiens 102-107 10918037-10 2000 O-Glycosylation of mucin-type sugar chains was not detected in recombinant soluble human L-selectin. Sugars 30-35 LOC100508689 Homo sapiens 19-24 10409676-4 1999 Structural analysis with use of lectin affinity high performance liquid chromatography revealed that typical mucin-type sugar chains of the glycoproteins from undifferentiated cells have H type 2 group, linear polylactosamines, and core 1 structure. Sugars 120-125 LOC100508689 Homo sapiens 109-114 10632536-7 2000 By ELISA using mucin in which the sugar chains were destroyed by neuraminidase or NaIO4 treatment, it was demonstrated that anti-mucin antibodies recognized the epitopes of either the sugar chain or the core protein exposed through destruction of the sugar chains. Sugars 34-39 LOC100508689 Homo sapiens 15-20 10632536-7 2000 By ELISA using mucin in which the sugar chains were destroyed by neuraminidase or NaIO4 treatment, it was demonstrated that anti-mucin antibodies recognized the epitopes of either the sugar chain or the core protein exposed through destruction of the sugar chains. Sugars 34-39 LOC100508689 Homo sapiens 129-134 10632536-7 2000 By ELISA using mucin in which the sugar chains were destroyed by neuraminidase or NaIO4 treatment, it was demonstrated that anti-mucin antibodies recognized the epitopes of either the sugar chain or the core protein exposed through destruction of the sugar chains. Sugars 184-189 LOC100508689 Homo sapiens 129-134 10632536-7 2000 By ELISA using mucin in which the sugar chains were destroyed by neuraminidase or NaIO4 treatment, it was demonstrated that anti-mucin antibodies recognized the epitopes of either the sugar chain or the core protein exposed through destruction of the sugar chains. Sugars 184-189 LOC100508689 Homo sapiens 129-134 10714169-0 2000 [Physiological role of mucin-type sugar chain on hinge portion of human serum IgA1]. Sugars 34-39 LOC100508689 Homo sapiens 23-28 10409676-8 1999 These results suggest that the mucin-type sugar chains with H type 1 group have important functions regarding differentiation of Caco-2 cells. Sugars 42-47 LOC100508689 Homo sapiens 31-36 8813123-3 1996 Galectin-3 bound to purified native and desialylated colon cancer mucin in a concentration-dependent manner, which was completely inhibited by 0.1 M lactose, the competitive inhibitory sugar for this protein. Sugars 185-190 LOC100508689 Homo sapiens 66-71 10358439-0 1999 [Strategy for analysis of blood group antigen on mucin-type sugar chains]. Sugars 60-65 LOC100508689 Homo sapiens 49-54 9504711-3 1998 Superposed on the genetic diversity, each type of mucin displays heterogeneity in oligosaccharide composition, including the terminal sugar residues. Sugars 134-139 LOC100508689 Homo sapiens 50-55 9218863-7 1997 The variety of chain locations and sugar attachment sites of sulphate esters on the mucin oligosaccharides, taken together with the data on the enzymes, suggest there will be a spectrum of bacterial glycosulphatases, with different properties, cellular locations and substrate specificities. Sugars 35-40 LOC100508689 Homo sapiens 84-89 8943259-5 1996 A monoclonal antibody specific for a mucin sugar epitope and a polyclonal serum directed to peptide epitopes in a MUC gene-encoded recombinant protein, detected identical bands in three out of seven strains of T. cruzi. Sugars 43-48 LOC100508689 Homo sapiens 37-42 8132328-4 1994 Periodate oxidation also did not alter bacterial adherence, indicating that vicinal hydroxyl groups in the mucin sugars are not important for binding. Sugars 113-119 LOC100508689 Homo sapiens 107-112 7588808-3 1995 The exposure of peptide epitopes is thus thought to be due to the sugar side chains being shorter on the tumour-associated mucin. Sugars 66-71 LOC100508689 Homo sapiens 123-128 7945335-0 1994 Production of monoclonal antibodies recognizing cancer-associated antigens expressed on mucin-type sugar chains. Sugars 99-104 LOC100508689 Homo sapiens 88-93 8132328-9 1994 After removal of terminal and backbone sugar residues by treatment of mucin with trifluoromethanesulfonic acid, binding of plasmid-bearing bacteria increased significantly when N-acetylgalactosamine, either alone or with galactose attached, was revealed, indicating that core regions of the sugar side chains are involved in bacterial binding. Sugars 39-44 LOC100508689 Homo sapiens 70-75 8132328-9 1994 After removal of terminal and backbone sugar residues by treatment of mucin with trifluoromethanesulfonic acid, binding of plasmid-bearing bacteria increased significantly when N-acetylgalactosamine, either alone or with galactose attached, was revealed, indicating that core regions of the sugar side chains are involved in bacterial binding. Sugars 291-296 LOC100508689 Homo sapiens 70-75 8460945-0 1993 Structures of mucin-type sugar chains on human erythropoietins purified from urine and the culture medium of recombinant Chinese hamster ovary cells. Sugars 25-30 LOC100508689 Homo sapiens 14-19 8218578-7 1993 Lectins combined with mucin histochemistry allowed visualization of specific sugar residues in the same glycol methacrylate plastic section. Sugars 77-82 LOC100508689 Homo sapiens 22-27 8460945-1 1993 Less is known about the mucin-type sugar chains attached to human erythropoietin as compared with N-linked sugar chains which structures and function have been well studied. Sugars 35-40 LOC100508689 Homo sapiens 24-29 3335536-0 1988 Comparative study of the mucin-type sugar chains of human chorionic gonadotropin present in the urine of patients with trophoblastic diseases and healthy pregnant women. Sugars 36-41 LOC100508689 Homo sapiens 25-30 34824233-6 2021 liberate diet- and mucin-derived sugars and Enterobacteriaceae spp. Sugars 33-39 LOC100508689 Homo sapiens 19-24 1415719-2 1992 The apparent expression of more than one type of oligosaccharide core structure in mucins isolated from pathological material may reflect either inherent limitations in analysis, disease-related alterations in parameters affecting glycosylation and post-translational modifications (e.g., nucleotide-sugar concentrations, expression of specific glycosyltransferases, rates of transport through the endoplasmic reticulum and Golgi) or the activation of mucin protein genes that are more highly expressed in disease states with different glycosylation patterns. Sugars 300-305 LOC100508689 Homo sapiens 83-88 1419961-1 1992 study of interaction between sugar and peptide moieties in mucin-type model glycopeptides. Sugars 29-34 LOC100508689 Homo sapiens 59-64 1663364-0 1991 Reactivity of mucin-specific lectin from Sambucus sieboldiana with simple sugars, normal mucins and tumor-associated mucins. Sugars 74-80 LOC100508689 Homo sapiens 14-19 2321937-5 1990 Mucin breakdown as measured by sugar analyses indicated that oligosaccharide chains were only partially degraded. Sugars 31-36 LOC100508689 Homo sapiens 0-5 2470396-3 1989 Sugar residues in the mucin of surface mucous cells seem to undergo no major changes throughout the period under study, since secretory granules of the cells were positive in periodic acid-Schiff (PAS) and galactose oxidase-Schiff (GOS) reactions and consistently bound certain lectins. Sugars 0-5 LOC100508689 Homo sapiens 22-27 2622352-0 1989 Quantitative conversion of mucin-type sugar chains to radioactive oligosaccharides. Sugars 38-43 LOC100508689 Homo sapiens 27-32 3192745-0 1988 Simple procedure for assessing relative quantities of neutral and acidic sugars in mucin glycoproteins: its use in assessing cyclical changes in cervical mucins. Sugars 73-79 LOC100508689 Homo sapiens 83-88 3192745-1 1988 A simple histochemical procedure for assessing relative amounts of neutral and acidic sugars in mucin glycoproteins, and its application in the study of cyclical changes of human cervical mucins, is described. Sugars 86-92 LOC100508689 Homo sapiens 96-101 3335536-1 1988 Human chorionic gonadotropins (hCGs) highly purified from the urine of patients with trophoblastic diseases and of healthy pregnant women contain approximately four mucin-type sugar chains in one molecule. Sugars 176-181 LOC100508689 Homo sapiens 165-170 3335536-2 1988 The structures of these sugar chains were studied comparatively by using a new sensitive method to obtain mucin-type sugar chains quantitatively as radioactive oligosaccharides from a small amount of glycoproteins. Sugars 24-29 LOC100508689 Homo sapiens 106-111 3335536-2 1988 The structures of these sugar chains were studied comparatively by using a new sensitive method to obtain mucin-type sugar chains quantitatively as radioactive oligosaccharides from a small amount of glycoproteins. Sugars 117-122 LOC100508689 Homo sapiens 106-111 3335536-3 1988 The mucin-type sugar chains of all hCGs include sialylated and nonsialylated Gal beta 1----3GalNAc and Gal beta 1----4GlcNAc beta 1----6(Gal beta 1----3)GalNAc. Sugars 15-20 LOC100508689 Homo sapiens 4-9 29408005-6 2018 The above are complemented by UV spectroscopy: A blue shift of the conjugated aminoacids in the presence of DMSO suggests that the inherent stability of mucin is not only due to steric volume exclusions, but also due to extensive hydrogen bonding on behalf of the sugar moieties. Sugars 264-269 LOC100508689 Homo sapiens 153-158 13422436-2 1956 Sugar components of snail mucus mucin. Sugars 0-5 LOC100508689 Homo sapiens 32-37 2985503-3 1985 The receptor on injured tracheal cells contains n-acetylneuraminic acid as the principal sugar, but the structure of the receptor in mucin has not been described. Sugars 89-94 LOC100508689 Homo sapiens 133-138 27590817-14 2016 The results of this study provide further evidence of the ability of this species to utilize mucin-derived sugars, a trait which may provide a competitive advantage in both the infant gut and adult gut. Sugars 107-113 LOC100508689 Homo sapiens 93-98 27741156-4 2016 In addition, these sugars promote adhesion of commensal bacterial strains to host cells as well as possessing the ability to alter mucin expression in intestinal cells and improve barrier function. Sugars 19-25 LOC100508689 Homo sapiens 131-136 28814130-2 2017 However, our knowledge about mucin type O-glycan degradation by bifidobacteria remains fragmentary, especially regarding how they decompose sulfated glycans, which are abundantly found in mucin sugar-chains. Sugars 194-199 LOC100508689 Homo sapiens 29-34 28814130-2 2017 However, our knowledge about mucin type O-glycan degradation by bifidobacteria remains fragmentary, especially regarding how they decompose sulfated glycans, which are abundantly found in mucin sugar-chains. Sugars 194-199 LOC100508689 Homo sapiens 188-193 26692014-9 2016 These findings indicate that clusters of both TR backbones and sugars are essential for mAb binding to mucin glycopeptides. Sugars 63-69 LOC100508689 Homo sapiens 103-108 25727146-0 2015 Simple sugars to complex disease--mucin-type O-glycans in cancer. Sugars 7-13 LOC100508689 Homo sapiens 34-39 26556271-5 2015 Experiments with media containing systematically varied carbohydrate cues and genetic mutants reveal that transcriptional repression of genes involved in mucin glycan metabolism is imposed by simple sugars and, in one example that was tested, is mediated through a small intergenic region in a transcript-autonomous fashion. Sugars 199-205 LOC100508689 Homo sapiens 154-159 25550518-7 2015 Applying this approach to mouse cecal microbiota revealed that the host-compound foragers Akkermansia muciniphila and Bacteroides acidifaciens exhibited distinctive response patterns to amendments of mucin and sugars. Sugars 210-216 LOC100508689 Homo sapiens 102-107 25727146-1 2015 Mucin-type O-glycans are a class of glycans initiated with N-acetylgalactosamine (GalNAc) alpha-linked primarily to Ser/Thr residues within glycoproteins and often extended or branched by sugars or saccharides. Sugars 188-194 LOC100508689 Homo sapiens 0-5