PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15374099-4 1997 The levels of MAP1B mRNA in the cortex of 3-month-old rats returned to control levels by 10 days after PTZ administration. Pentylenetetrazole 103-106 microtubule-associated protein 1B Rattus norvegicus 14-19 10579203-0 1999 Anomalous expression of microtubule-associated protein 1B in the hippocampus and cortex of aged rats treated with pentylenetetrazole. Pentylenetetrazole 114-132 microtubule-associated protein 1B Rattus norvegicus 24-57 10579203-2 1999 The effect of a single administration of the convulsant pentylenetetrazole on microtubule-associated protein 1B expression in the hippocampal formation and cortex of three-, 18- and 28-month-old rats was assessed using northern blot analysis, in situ hybridization and immunohistochemistry. Pentylenetetrazole 56-74 microtubule-associated protein 1B Rattus norvegicus 78-111 10579203-4 1999 However, following pentylenetetrazole treatment in older rats, the granule cells of the dentate gyrus were nearly devoid of microtubule-associated protein 1B immunoreactivity, whereas the retrosplenial cortex showed no changes at all, and the entorhinal cortex had an expression pattern similar to that of young rats. Pentylenetetrazole 19-37 microtubule-associated protein 1B Rattus norvegicus 124-157 9512009-0 1998 Altered expression of microtubule-associated protein 1B in cerebral cortical structures of pentylenetetrazole-treated rats. Pentylenetetrazole 91-109 microtubule-associated protein 1B Rattus norvegicus 22-55 9512009-1 1998 Using Northern blot, immunoblotting, immunocytochemistry, and in situ hybridization, we show that a single administration of the convulsant pentylenetetrazole leads to robust, long-term changes in microtubule-associated protein 1B and its mRNA, in the adult rat brain. Pentylenetetrazole 140-158 microtubule-associated protein 1B Rattus norvegicus 197-230 9512009-2 1998 The first increases in MAP1B mRNA were detected at 15 hr following pentylenetetrazole administration in the temporal (Te2) and perirhinal cortex followed by increases in microtubule-associated protein 1B immunoreactivity at 72 hr postseizure. Pentylenetetrazole 67-85 microtubule-associated protein 1B Rattus norvegicus 23-28 9398451-0 1997 Increased expression of microtubule-associated protein 1B in the hippocampus, subiculum, and perforant path of rats treated with a high dose of pentylenetetrazole. Pentylenetetrazole 144-162 microtubule-associated protein 1B Rattus norvegicus 24-57 9398451-1 1997 A single administration of the convulsant pentylenetetrazole (PTZ) initiates a complex pattern of long-term changes in microtubule-associated protein 1B (MAP1B) expression across the hippocampal formation. Pentylenetetrazole 42-60 microtubule-associated protein 1B Rattus norvegicus 119-152 9398451-1 1997 A single administration of the convulsant pentylenetetrazole (PTZ) initiates a complex pattern of long-term changes in microtubule-associated protein 1B (MAP1B) expression across the hippocampal formation. Pentylenetetrazole 42-60 microtubule-associated protein 1B Rattus norvegicus 154-159 9398451-1 1997 A single administration of the convulsant pentylenetetrazole (PTZ) initiates a complex pattern of long-term changes in microtubule-associated protein 1B (MAP1B) expression across the hippocampal formation. Pentylenetetrazole 62-65 microtubule-associated protein 1B Rattus norvegicus 119-152 9398451-1 1997 A single administration of the convulsant pentylenetetrazole (PTZ) initiates a complex pattern of long-term changes in microtubule-associated protein 1B (MAP1B) expression across the hippocampal formation. Pentylenetetrazole 62-65 microtubule-associated protein 1B Rattus norvegicus 154-159 9398451-2 1997 Using Northern blot and in situ hybridization we show that the first increases in MAP1B mRNA were detected at 15 h following PTZ administration in the granule cells of the dentate gyrus and CA3 region of the hippocampus and reached a maximum at 44 h. The levels of MAP1B mRNA in the subiculum peaked at later times (5 days). Pentylenetetrazole 125-128 microtubule-associated protein 1B Rattus norvegicus 82-87 9398451-2 1997 Using Northern blot and in situ hybridization we show that the first increases in MAP1B mRNA were detected at 15 h following PTZ administration in the granule cells of the dentate gyrus and CA3 region of the hippocampus and reached a maximum at 44 h. The levels of MAP1B mRNA in the subiculum peaked at later times (5 days). Pentylenetetrazole 125-128 microtubule-associated protein 1B Rattus norvegicus 265-270 9398451-5 1997 The levels of MAP1B in the hippocampus returned to control levels by 20 days after PTZ administration. Pentylenetetrazole 83-86 microtubule-associated protein 1B Rattus norvegicus 14-19 9398451-8 1997 Our studies show that (i) MAP1B is a temporal and regional marker for rapid and acute epileptic seizures and (ii) long-term increases in MAP1B in the perforant path might play a role in PTZ-induced seizures. Pentylenetetrazole 186-189 microtubule-associated protein 1B Rattus norvegicus 26-31 9398451-8 1997 Our studies show that (i) MAP1B is a temporal and regional marker for rapid and acute epileptic seizures and (ii) long-term increases in MAP1B in the perforant path might play a role in PTZ-induced seizures. Pentylenetetrazole 186-189 microtubule-associated protein 1B Rattus norvegicus 137-142 15374099-5 1997 The levels of MAP1B mRNA in the hippocampus and cortex of 20 months at later times (10 days) and returned nearly to basal levels by 20 days following PTZ treatment. Pentylenetetrazole 150-153 microtubule-associated protein 1B Rattus norvegicus 14-19 7790894-0 1995 Pentylenetetrazole-induced seizure up-regulates levels of microtubule-associated protein 1B mRNA and protein in the hippocampus of the rat. Pentylenetetrazole 0-18 microtubule-associated protein 1B Rattus norvegicus 58-91 7790894-5 1995 The levels of MAP1B mRNA in hippocampus peaked at 40 h and began to decline by 72 h following PTZ treatment. Pentylenetetrazole 94-97 microtubule-associated protein 1B Rattus norvegicus 14-19 7790894-6 1995 Immunoblotting with anti-MAP1B antibody demonstrates the increase in content of immunoreactive proteins 40-72 h after seizure onset in the hippocampus of PTZ-treated rats. Pentylenetetrazole 154-157 microtubule-associated protein 1B Rattus norvegicus 25-30 7790894-7 1995 These results indicate that MAP1B is a sensitive indicator of hippocampal structural changes occurring in response to PTZ-induced seizure activity. Pentylenetetrazole 118-121 microtubule-associated protein 1B Rattus norvegicus 28-33