PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10910964-0	2000	Effect of chlorinated hydrocarbons on expression of cytochrome P450 1A1, 1A2 and 1B1 and 2- and 4-hydroxylation of 17beta-estradiol in female Sprague-Dawley rats.	Hydrocarbons	22-34	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	52-90	
8246922-2	1993	The P-450s assessed included the polyaromatic hydrocarbon-inducible CYP1A1 and CYP1A2 systems, together with the phenobarbital-inducible P-450s, CYP2B1, CYP2B2, CYP3A1, which were examined 18 hr after a single intraperitoneal dose of the respective inducing agents.	Hydrocarbons	46-57	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	68-74	
9550098-6	1997	Since these enzymes (EROD, CYP 1A1/2 and PROD, CYP2B1) activate polycyclic hydrocarbons, aromatic amines and aliphatic halogenated hydrocarbons to their ultimate mutagenic or carcinogenic forms, and are effective in producing reactive oxygen species such as superoxide, hydroxyl radical and hydrogen peroxide, the new compound, BITN, appears to have a greater anticarcinogenic and antioxidant potential than RA and BHT.	Hydrocarbons	75-87	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	27-34	
9550098-6	1997	Since these enzymes (EROD, CYP 1A1/2 and PROD, CYP2B1) activate polycyclic hydrocarbons, aromatic amines and aliphatic halogenated hydrocarbons to their ultimate mutagenic or carcinogenic forms, and are effective in producing reactive oxygen species such as superoxide, hydroxyl radical and hydrogen peroxide, the new compound, BITN, appears to have a greater anticarcinogenic and antioxidant potential than RA and BHT.	Hydrocarbons	131-143	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	27-34	
1374249-4	1992	Using purified isoenzymes in an enzyme-linked immunosorbent assay it was found that the affinity of binding to the two rabbit hydrocarbon-inducible isoenzymes is reduced compared with that for rat CYP1A1.	Hydrocarbons	126-137	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	197-203	
6611202-2	1984	We prepared a monoclonal antibody (MAb 1-7-1) to a polycyclic hydrocarbon-induced rat cytochrome P-450 that antigenically defines and inhibits a type of cytochrome P-450 responsible for aryl hydrocarbon hydroxylase (AHH) and 7-ethoxycoumarin deethylase (ECD) activity in human placenta.	Hydrocarbons	62-73	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	186-214	
2306261-3	1990	Following treatment with hydrocarbons such as 3-methylcholanthrene (MC) and isosafrole (ISF) both cytochromes P450c (P450IA1) and P450d (P450IA2) are also induced in rat liver.	Hydrocarbons	25-37	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	110-115	
3178886-1	1988	An antibody that reacts with two hydrocarbon-inducible isoenzymes of rat cytochrome P-450 (c and d) in the rat was produced by immunising with a synthetic peptide, Leu-Ile-Ser-Lys-Phe-Gln-Lys-Leu-Met, which has the same primary structure as that of a region of both of these isoenzymes.	Hydrocarbons	33-44	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	73-98	
6210189-1	1984	The Aryl hydrocarbon hydroxylase (AHH) activity in the lavaged PAMs was investigated in male Fischer rats after inhalation of diluted diesel exhaust (DE), and compared with intratracheal instillation of the organic solvent extract of hydrocarbons adsorbed on the particulate surface.	Hydrocarbons	234-246	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	34-37	
6611202-2	1984	We prepared a monoclonal antibody (MAb 1-7-1) to a polycyclic hydrocarbon-induced rat cytochrome P-450 that antigenically defines and inhibits a type of cytochrome P-450 responsible for aryl hydrocarbon hydroxylase (AHH) and 7-ethoxycoumarin deethylase (ECD) activity in human placenta.	Hydrocarbons	62-73	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	216-219	
6430894-4	1984	In the second approach, each hydrocarbon was incubated with a reconstituted system containing both cytochrome P-450c and epoxide hydrolase.	Hydrocarbons	29-40	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	99-116