PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11577022-4 2001 Although Cyp1a1 was inducible in Ahr(+/+) by 3 micromol/L benzo(a)pyrene, a known hydrocarbon inducer, the protein was uninducible. Hydrocarbons 82-93 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 9-15 106274-9 1979 AR and MC are very good inducers of AHH activity in livers of mice classified as aromatic hydrocarbon responsive, but not in those classified as hydrocarbon nonresponsive. Hydrocarbons 90-101 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 36-39 6690048-1 1984 In mice, there is a correlation between genetically regulated levels of inducible aryl hydrocarbon hydroxylase (AHH) activity and the risk of polycyclic hydrocarbon-induced leukemia or solid tumors. Hydrocarbons 87-98 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 112-115 7460072-9 1981 The 5--10-fold difference between cells from responsive and non-responsive mice in concentration of 3-MC needed to induce AHH maximally is taken to indicate that genes controlling aromatic hydrocarbon responsiveness in adult mouse livers in vivo also function in fetal mouse liver cells maintained in culture. Hydrocarbons 189-200 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 122-125 11163336-4 2001 2,3,7,8-Tetrachlorodibenzo-p-dioxin (dioxin; TCDD) is known to activate Cyp1a1 gene transcription by way of aromatic hydrocarbon response elements (AHREs). Hydrocarbons 117-128 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 72-78 1692256-9 1990 Our observations indicate that, although AHH induction was genetically determined in each strain, activity can be induced in hepatocytes of so-called nonresponsive as well as responsive mouse strains by treatment with aromatic hydrocarbons after transfer of the cells to primary culture. Hydrocarbons 227-239 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 41-44 14720319-7 2004 Significantly, gene expression of CYP1A1 and 1B1 is induced by PAHs and polyhalogenated hydrocarbons such as 2,3,7,8-tetrachlorodibenzo-p-dioxin through the arylhydrocarbon receptor. Hydrocarbons 88-100 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 34-48 20930378-6 2010 The present observations suggest the need to reveal the mechanism by which CYP1A1 expression is modified by flavonoids for risk assessment, since CYP1A1 activates environmental carcinogenic polycyclic hydrocarbons and flavonoids are major constituents in food. Hydrocarbons 201-213 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 75-81 20930378-6 2010 The present observations suggest the need to reveal the mechanism by which CYP1A1 expression is modified by flavonoids for risk assessment, since CYP1A1 activates environmental carcinogenic polycyclic hydrocarbons and flavonoids are major constituents in food. Hydrocarbons 201-213 cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus 146-152