PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31616405-6	2019	Following priming with LPS, both the canonical activator nigericin and cSiO2 elicited robust inflammasome activation in RAW-ASC cells, as reflected by IL-1beta release and caspase-1 activation.	Nigericin	57-66	steroid sulfatase	Mus musculus	120-127	
33123123-8	2020	Furthermore, MPI effector cells could likewise engulf RAW-ASC target cell corpses elicited by treatment with staurosporine (apoptosis), LPS, and nigericin (pyroptosis), or cSiO2.	Nigericin	145-154	steroid sulfatase	Mus musculus	54-61	
32733353-9	2020	Nigericin administration enhanced ASC oligomerization, caspase-1 and IL-1beta maturation without increasing the protein level of NLRP3, and ASC oligomerization and caspase-1 IL-1beta maturation reduced when combined with NEK7 knockdown or MCC950 delivery.	Nigericin	0-9	steroid sulfatase	Mus musculus	34-37	
31936823-6	2020	Importantly, we observed that IL-37 suppresses nigericin- and silica-induced ASC oligomerization/speck formation (a step in inflammasome activation and subsequent caspase-1 activation), and pyroptosis (-50%).	Nigericin	47-56	steroid sulfatase	Mus musculus	77-80	
30761140-3	2019	Here we showed that paclitaxel pre-treatment greatly enhanced ATP- or nigericin-induced NLRP3 inflammasome activation as indicated by increased release of cleaved caspase-1 and mature IL-1beta, enhanced formation of ASC speck, and increased gasdermin D cleavage and pyroptosis.	Nigericin	70-79	steroid sulfatase	Mus musculus	216-219	
29863661-12	2018	In this manuscript, we show that activation of the NLRP3 inflammasome by nigericin leads to the co-localization of the adaptor protein ASC and active caspase-1, leading to pyroptosis.	Nigericin	73-82	steroid sulfatase	Mus musculus	135-138