PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31632394-6	2019	Using the NLRP3 inflammasome-deficient Raw 264.7 and PYCARD-deficient J77 macrophages, which both lack PYCARD, we found that the potassium efflux activator nigericin enhances bacterial killing.	Nigericin	156-165	PYD and CARD domain containing	Homo sapiens	53-59	
34830395-5	2021	Using our method to measure ASC, stimulation of PBMC with lipopolysaccharide and nigericin or adenosine triphosphate resulted in microscopic identification of intracellular ASC specks, as well as interleukin 1 (IL-1) beta and caspase-1 p10 in the periphery.	Nigericin	81-90	PYD and CARD domain containing	Homo sapiens	28-31	
34830395-5	2021	Using our method to measure ASC, stimulation of PBMC with lipopolysaccharide and nigericin or adenosine triphosphate resulted in microscopic identification of intracellular ASC specks, as well as interleukin 1 (IL-1) beta and caspase-1 p10 in the periphery.	Nigericin	81-90	PYD and CARD domain containing	Homo sapiens	173-176	
32445196-5	2020	Nigericin-induced NLRP3 inflammasome activation was dynamically visualised in microglia through ASC speck formation.	Nigericin	0-9	PYD and CARD domain containing	Homo sapiens	96-99	
29479354-7	2018	To further understand the differential expression of cytokines/chemokines, we showed that WFA alters the nigericin-induced co-localization of NLRP3 and ASC proteins, thereby inhibiting caspase-1 activation, which is responsible for the cleavage and maturation of pro-inflammatory cytokines IL-1beta and IL-18.	Nigericin	105-114	PYD and CARD domain containing	Homo sapiens	152-155	
30513737-9	2018	Moreover, this strong reduction of pro-inflammatory IL-1beta is associated with a decrease of NLRP3 and, in J774A, ASC protein expression, which depends on the choice of activator ATP or nigericin.	Nigericin	187-196	PYD and CARD domain containing	Homo sapiens	115-118	
31214205-7	2019	Here we explored the optimal imaging-based tools to measure ASC speck formation via imaging flow cytometry by using peripheral blood mononuclear cells (PBMCs) stimulated with the NLRP3 agonist Nigericin, as a positive control.	Nigericin	193-202	PYD and CARD domain containing	Homo sapiens	60-63	
28787755-3	2017	Interestingly, GW4064 decreases the nigericin-induced oligomerization and ubiquitination of ASC which is critical for the NLRP3 inflammasome activation.	Nigericin	36-45	PYD and CARD domain containing	Homo sapiens	92-95	
27431477-6	2016	In ATP- or nigericin-activated macrophages, our data further indicate that Flightless-I (FliI) and leucine-rich repeat FliI-interaction protein 2 (LRRFIP2) are required for the co-localization of NLRP3, ASC and F-actin.	Nigericin	11-20	PYD and CARD domain containing	Homo sapiens	203-206