PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33232283-11	2020	Finally, in vitro studies revealed that the NLRP3 activator nigericin abolished the anti-inflammatory effects of metformin in NRVMs, but it had little effect on AMPK phosphorylation.	Nigericin	60-69	NLR family, pyrin domain containing 3	Rattus norvegicus	44-49	
33777317-9	2021	In order to identify the potential mechanisms, we further revealed that nigericin administration reversed the neuroprotective effect of melatonin by promoting NLRP3 inflammasome activation.	Nigericin	72-81	NLR family, pyrin domain containing 3	Rattus norvegicus	159-164	
34434260-3	2021	CCI rats were treated with DEX, the nuclear factor erythroid 2-related factor 2 (Nrf2) inhibitor ML385, the NLR family pyrin domain containing 3 (NLRP3) antagonist MCC950 and/or the NLRP3 activator nigericin.	Nigericin	198-207	NLR family, pyrin domain containing 3	Rattus norvegicus	182-187	
34432650-13	2021	NLRP3 inflammasome activation by nigericin-induced cardiocytes cells aging progress.	Nigericin	33-42	NLR family, pyrin domain containing 3	Rattus norvegicus	0-5	
35126093-6	2021	Subsequently, we established the D-gal and Nigericin-induced PC12 cells injury model in vitro to verify Sal blocks pyroptosis mainly by targeting the NLRP3 inflammasome.	Nigericin	43-52	NLR family, pyrin domain containing 3	Rattus norvegicus	150-155	
33568649-7	2021	Nifedipine D6 was added to H/R-induced cells to block Ca2+ channel or Nigericin was added to activate NLRP3.	Nigericin	70-79	NLR family, pyrin domain containing 3	Rattus norvegicus	102-107	
33974557-10	2021	Furthermore, MCC950 decreased the PRL expression and secretion following the inhibition of NLRP3 inflammasome activation in GH3 cells stimulated with lipopolysaccharide and nigericin and in prolactinoma rats.	Nigericin	173-182	NLR family, pyrin domain containing 3	Rattus norvegicus	91-96