PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26892147-9 2016 A microarray analysis showed that ATRA plus ATO treatment markedly down-regulated the expression of proteinase 3 (PRTN3), which is involved in the differentiation arrest of leukemia cells, compared with treatment with ATRA alone. Arsenic Trioxide 44-47 proteinase 3 Homo sapiens 100-112 26892147-9 2016 A microarray analysis showed that ATRA plus ATO treatment markedly down-regulated the expression of proteinase 3 (PRTN3), which is involved in the differentiation arrest of leukemia cells, compared with treatment with ATRA alone. Arsenic Trioxide 44-47 proteinase 3 Homo sapiens 114-119 26892147-10 2016 The PRTN3 mRNA level was suppressed by treatment with ATRA alone, and then further suppressed by co-treatment with ATO, accompanied by a concomitant increase in Sp1 protein, which is known to facilitate differentiation. Arsenic Trioxide 115-118 proteinase 3 Homo sapiens 4-9