PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21847655-4	2011	High expression of JWA promoted tubulin polymerization and increased the sensitivity of the cancer cells to As2O3.	Arsenic Trioxide	108-113	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	19-22	
21847655-0	2011	JWA enhances As2O3-induced tubulin polymerization and apoptosis via p38 in HeLa and MCF-7 cells.	Arsenic Trioxide	13-18	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	0-3	
21847655-6	2011	Our results suggest that JWA may serve as an effective enhancer of microtubule-targeted As2O3 anti-cancer therapy.	Arsenic Trioxide	88-93	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	25-28	
18387645-0	2008	JWA is required for arsenic trioxide induced apoptosis in HeLa and MCF-7 cells via reactive oxygen species and mitochondria linked signal pathway.	Arsenic Trioxide	20-36	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	0-3	
19946336-1	2010	JWA, a newly identified novel microtubule-associated protein (MAP), was recently demonstrated to be indispensable for the rearrangement of actin cytoskeleton and activation of MAPK cascades induced by arsenic trioxide (As(2)O(3)) and phorbol ester (PMA).	Arsenic Trioxide	201-217	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	0-3	
19492242-2	2009	Our previous studies demonstrated that JWA is a pro-apoptotic molecule and required for arsenic trioxide and all-trans-retinoic acid-induced cancer cell apoptosis.	Arsenic Trioxide	88-104	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	39-42	
18387645-2	2008	JWA, a novel retinoic acid-inducible gene, is known to be involved in apoptosis induced by various agents, for example, 12-O-tetradecanoylphorbol 13-acetate, N-4-hydroxy-phenyl-retinamide and arsenic trioxide.	Arsenic Trioxide	192-208	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	0-3	
18387645-4	2008	Herein, our studies demonstrated that treatment of arsenic trioxide produced apoptosis in HeLa and MCF-7 cells in a dose-dependent manner and paralleled with increased JWA expression.	Arsenic Trioxide	51-67	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	168-171	
18387645-5	2008	JWA expression was dependent upon generation of intracellular reactive oxygen species induced by arsenic trioxide.	Arsenic Trioxide	97-113	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	0-3	
18387645-6	2008	Knockdown of JWA attenuated arsenic trioxide induced apoptosis, and was accompanied by significantly reduced activity of caspase-9, enhanced Bad phosphorylation and inhibited MEK1/2, ERK1/2 and JNK phosphorylations.	Arsenic Trioxide	28-44	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	13-16	
18387645-7	2008	Arsenic trioxide induced loss of mitochondrial transmembrane potential was JWA-dependent.	Arsenic Trioxide	0-16	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	75-78	
18387645-8	2008	These findings suggest that JWA may serve as a pro-apoptotic molecule to mediate arsenic trioxide triggered apoptosis via a reactive oxygen species and mitochondria-associated signal pathway.	Arsenic Trioxide	81-97	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	28-31	
17336041-3	2007	Data in this study show that JWA, a newly identified novel microtubule-associated protein (MAP) was essential for the rearrangement of F-actin cytoskeleton and activation of MAPK cascades induced by arsenic trioxide (As2O3) and phorbol ester (PMA).	Arsenic Trioxide	199-215	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	29-32	
17336041-3	2007	Data in this study show that JWA, a newly identified novel microtubule-associated protein (MAP) was essential for the rearrangement of F-actin cytoskeleton and activation of MAPK cascades induced by arsenic trioxide (As2O3) and phorbol ester (PMA).	Arsenic Trioxide	217-222	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	29-32