PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31132733-0 2019 L-Fucose ameliorates DSS-induced acute colitis via inhibiting macrophage M1 polarization and inhibiting NLRP3 inflammasome and NF-kB activation. Fucose 0-8 NLR family pyrin domain containing 3 Homo sapiens 104-109 31132733-5 2019 In addition, L-fucose can inhibit macrophage M1 polarization, inactivate the NLRP3 inflammasome and reduce the release of TNFalpha, IL1beta, IL6 pro-inflammatory cytokines. Fucose 13-21 NLR family pyrin domain containing 3 Homo sapiens 77-82 31132733-6 2019 In vitro studies showed that L-fucose ameliorated cell damage resulting from the administration of LPS with ATP in BMDMs, inhibited NLRP3 inflammasome activation and reduced the release of corresponding pro-inflammatory cytokines. Fucose 29-37 NLR family pyrin domain containing 3 Homo sapiens 132-137 31132733-8 2019 Overall, our results show that L-fucose can attenuate colitis by inhibiting macrophage M1 polarization, inhibiting NLRP3 inflammasome and NF-kB activation, and down-regulation of pro-inflammatory cytokines. Fucose 31-39 NLR family pyrin domain containing 3 Homo sapiens 115-120