PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17253824-1 2007 Chemoselective SN2" condensation of primary enolates of alkyl methyl ketones 2a-e with dimethyl bromomethylfumarate (1) followed by highly diastereoselective NaBH4 reduction of the ketone function in the formed ketodiesters 3a-e and the regioselective in situ lactonization of the unisolable intermediates 4a-e exclusively furnished the cis-3,5-disubstituted gamma-butyrolactones (+/-)-5a-e in very good yields. sodium borohydride 158-163 solute carrier family 38 member 5 Homo sapiens 15-18