PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15459111-5 2005 We also found that hCG coordinately up-regulated the expression of Mvk and other sterol-responsive elements containing cholesterol biosynthesis enzymes, such as 3-hydroxy-3-methylglutaryl-coenzyme A synthase, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, and farnesyl pyrophosphate synthase. Sterols 81-87 farnesyl diphosphate synthase Rattus norvegicus 262-293 8570665-3 1996 Mutation of three nucleotides (CAC) within this element blocks the 8-fold induction of FPP synthase promoter-reporter genes that normally occurs when the transfected cells are incubated in medium deprived of sterols. Sterols 208-215 farnesyl diphosphate synthase Rattus norvegicus 87-99 8570665-7 1996 Coexpression of SREBP with a wild-type FPP synthase promoter-reporter gene in CV-1 cells results in very high levels of reporter activity that is sterol-independent. Sterols 146-152 farnesyl diphosphate synthase Rattus norvegicus 39-51 10484604-1 1999 Farnesyl diphosphate synthase (FPPS: EC2.5.1.10), a key enzyme in isoprenoid metabolic pathways, catalyzes the synthesis of farnesyl diphosphate (FPP) an intermediate in the biosynthesis of both sterol and non-sterol isoprenoid end products. Sterols 195-201 farnesyl diphosphate synthase Rattus norvegicus 0-29