PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15868936-0	2005	Ellagic acid induced p53/p21 expression, G1 arrest and apoptosis in human bladder cancer T24 cells.	Ellagic Acid	0-12	tumor protein p53	Homo sapiens	21-24	
33381593-5	2020	Further research found ellagic acid and corilagin induced G2 phase cell cycle arrest by upregulating levels of P53, Bcl-2, caspase 3, and caspase 9, while the Bax was reduced.	Ellagic Acid	23-35	tumor protein p53	Homo sapiens	111-114	
27261574-0	2016	Curcumin and Ellagic acid synergistically induce ROS generation, DNA damage, p53 accumulation and apoptosis in HeLa cervical carcinoma cells.	Ellagic Acid	13-25	tumor protein p53	Homo sapiens	77-80	
27261574-5	2016	Besides this, Curcumin and Ellagic acid also restore p53, induce ROS formation and DNA damage.	Ellagic Acid	27-39	tumor protein p53	Homo sapiens	53-56	
23554011-7	2014	Western blotting assay showed that ellagic acid promoted p21, p53 and decreased CDC2 and WEE1 for leading to G0/G1 phase arrest and promoting BAD expression, AIF and Endo G, cytochrome c, caspase-9 and -3 for leading to apoptosis in TSGH8301 cells.	Ellagic Acid	35-47	tumor protein p53	Homo sapiens	62-65	
15868936-6	2005	Ellagic acid also increased p53 and p21 and decreased CDK2 gene expression, that may lead to the G0/G1 arrest of T24 cells.	Ellagic Acid	0-12	tumor protein p53	Homo sapiens	28-31	
15735102-4	2005	We found that quercetin and combinations of quercetin and ellagic acid nonsynergistically increased p53 protein levels.	Ellagic Acid	58-70	tumor protein p53	Homo sapiens	100-103	
15735102-5	2005	In contrast, ellagic acid potentiated the effects of quercetin for p21(cip1/waf1) protein levels and p53 phosphorylation at serine 15, possibly explaining the synergistic effect observed in apoptosis induction.	Ellagic Acid	13-25	tumor protein p53	Homo sapiens	101-104	
15735102-0	2005	Ellagic acid potentiates the effect of quercetin on p21waf1/cip1, p53, and MAP-kinases without affecting intracellular generation of reactive oxygen species in vitro.	Ellagic Acid	0-12	tumor protein p53	Homo sapiens	66-69	
15735102-10	2005	In summary, quercetin and ellagic acid combined increase the activation of p53 and p21(cip1/waf1) and the MAP kinases, JNK1,2 and p38, in a more than additive manner, suggesting a mechanism by which quercetin and ellagic acid synergistically induce apoptosis in cancer cells.	Ellagic Acid	26-38	tumor protein p53	Homo sapiens	75-78	
10355751-0	1999	p53/p21(WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells.	Ellagic Acid	82-94	tumor protein p53	Homo sapiens	0-3	
11299762-5	2001	Collectively, these observations suggest that growth inhibition by ellagic acid is mediated by signaling pathways that mediate DNA damage, triggers p53, which in turn activates p21 and at the same time alters the growth factor expression, resulting in the down regulation of IGF-II.	Ellagic Acid	67-79	tumor protein p53	Homo sapiens	148-151