PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33922395-7 2021 Moreover, ellagic acid (EA) inhibited the TGF-beta signaling pathway both in vitro and in vivo by reducing Smad2, Smad3, and Smad4 expression and thereby resensitized GCB sensitivity. Ellagic Acid 10-22 SMAD family member 3 Homo sapiens 114-119 32468010-0 2020 Ellagic acid induces cell cycle arrest and apoptosis via the TGF-beta1/Smad3 signaling pathway in human colon cancer HCT-116 cells. Ellagic Acid 0-12 SMAD family member 3 Homo sapiens 71-76 25647396-0 2015 Ellagic acid induces cell cycle arrest and apoptosis through TGF-beta/Smad3 signaling pathway in human breast cancer MCF-7 cells. Ellagic Acid 0-12 SMAD family member 3 Homo sapiens 70-75 24528038-0 2014 Ellagic acid exerts anti-proliferation effects via modulation of Tgf-beta/Smad3 signaling in MCF-7 breast cancer cells. Ellagic Acid 0-12 SMAD family member 3 Homo sapiens 74-79 24528038-3 2014 In this study, our aim was to investigate whether ellagic acid inhibits the proliferation of MCF- 7 human breast cancer cells via regulation of the TGF-beta/Smad3 signaling pathway. Ellagic Acid 50-62 SMAD family member 3 Homo sapiens 157-162 24528038-9 2014 Moreover, SIS3 reversed the effects of ellagic acid on the expression of downstream targets of the TGF-beta/Smad3 pathway. Ellagic Acid 39-51 SMAD family member 3 Homo sapiens 108-113 24528038-10 2014 In conclusion, ellagic acid leads to decreased phosphorylation of RB proteins mainly through modulation of the TGF-beta/Smad3 pathway, and thereby inhibits the proliferation of MCF-7 breast cancer cells. Ellagic Acid 15-27 SMAD family member 3 Homo sapiens 120-125 33922395-7 2021 Moreover, ellagic acid (EA) inhibited the TGF-beta signaling pathway both in vitro and in vivo by reducing Smad2, Smad3, and Smad4 expression and thereby resensitized GCB sensitivity. Ellagic Acid 24-26 SMAD family member 3 Homo sapiens 114-119