PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19812345-0	2009	Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine- and cAMP-induced CREB-dependent gene transcription.	Dopamine	70-78	cAMP responsive element binding protein 1	Mus musculus	97-101	
22419037-3	2012	We find that the basally-induced decrease in this phosphoprotein is the result of recruitment of the striatal dopamine D2 pathway, as evidenced by enhanced levels of D2 receptor (D2R) mRNA expression and D2R function as examined using the D2R antagonist, eticlopride, as well as alterations in the phosphorylation status of several downstream molecular targets of D2R"s, including CREB, DARPP-32, Akt and GSK3beta.	Dopamine	110-118	cAMP responsive element binding protein 1	Mus musculus	381-385	
19932712-7	2010	Then, we also examined the expression of transcription factor, dopamine markers and oxidative stress marker in the hippocampus of sensitive strain C3H/HeN mice and found that the expression of CREB1 mRNA was significantly increased at 50 ppm toluene.	Dopamine	63-71	cAMP responsive element binding protein 1	Mus musculus	193-198	
24790206-6	2014	Using Designer Receptors Exclusively Activated by Designer Drugs (DREADD) technology, we showed that selectively increasing cAMP levels in VTA dopamine neurons increased phosphorylation of TH at Ser40 and CREB at Ser133 and reversed behavioral deficits induced by Cdk5 deletion.	Dopamine	143-151	cAMP responsive element binding protein 1	Mus musculus	205-209	
24695708-7	2014	The RIalphaB-expressing mice also exhibit decreased locomotor activity and decreased dopamine-regulated CREB phosphorylation and c-fos gene expression in the striatum.	Dopamine	85-93	cAMP responsive element binding protein 1	Mus musculus	104-108	
9748539-3	1998	Phosphorylated-CREB (P-CREB) immunoreactivity in response to the dopamine D1 agonist (+/-)SKF 38393 (15 mg/kg, i.p.)	Dopamine	65-73	cAMP responsive element binding protein 1	Mus musculus	15-19	
15018806-0	2002	In vivo CREB phosphorylation mediated by dopamine and NMDA receptor activation in mouse hippocampus and caudate nucleus.	Dopamine	41-49	cAMP responsive element binding protein 1	Mus musculus	8-12	
14622103-0	2003	Differential distribution of CREB in the mesolimbic dopamine reward pathway.	Dopamine	52-60	cAMP responsive element binding protein 1	Mus musculus	29-33	
9748539-3	1998	Phosphorylated-CREB (P-CREB) immunoreactivity in response to the dopamine D1 agonist (+/-)SKF 38393 (15 mg/kg, i.p.)	Dopamine	65-73	cAMP responsive element binding protein 1	Mus musculus	23-27	
34001860-4	2021	Moreover, DA-DRD5 signaling can inhibit M1 by negatively regulating NF-kappaB signaling but promote M2 macrophage polarization through activation of the CREB pathway, respectively.	Dopamine	10-12	cAMP responsive element binding protein 1	Mus musculus	153-157	
35104500-4	2022	METHODS: GPCR-targeted piggyBac-TANGO compound screening system, cAMP assay, and immunostaining of p-CREB and BDNF were used to identify dopamine 2 receptor (DRD2) activation.	Dopamine	137-145	cAMP responsive element binding protein 1	Mus musculus	101-105	
33162095-8	2021	The research revealed that the GABAB-cyclic AMP-protein kinase A-cAMP-response element binding protein (GABAB-cAMP-PKA-CREB) signaling pathway was related to the depression-like symptoms and that levels of 5-hydroxytryptamine, norepinephrine, and dopamine in the hippocampus of mice increased after treatment with the adzuki bean sprout fermented milk.	Dopamine	247-255	cAMP responsive element binding protein 1	Mus musculus	119-123	
32800853-0	2020	Activation of AMPK/aPKCzeta/CREB pathway by metformin is associated with upregulation of GDNF and dopamine.	Dopamine	98-106	cAMP responsive element binding protein 1	Mus musculus	28-32	
31425745-11	2019	The results revealed that danshensu treatment significantly improved scopolamine and Abeta-induced cognitive impairments in mice by facilitation of dopamine signaling cascade such as PKA and CREB due to MAO-A inhibition.	Dopamine	148-156	cAMP responsive element binding protein 1	Mus musculus	191-195