PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15934928-7	2005	In addition, reduced BDNF expression causes decreased dopamine receptor expression in mutant huntingtin mice.	Dopamine	54-62	huntingtin	Mus musculus	93-103	
16019264-5	2005	The reduction in mHtt was concomitant with a reduction in the size and number of neuronal intranuclear inclusions and a small but significant normalization of the steady-state levels of preproenkephalin and dopamine- and cAMP-responsive phosphoprotein 32 kDa mRNA.	Dopamine	207-215	huntingtin	Mus musculus	17-21	
22363539-12	2012	Finally, we show that mutant HTT suppresses some Mn-dependent changes, such as decreased DA levels, while it exacerbates others, such as dendritic pathology.	Dopamine	89-91	huntingtin	Mus musculus	29-32	
17065224-0	2006	Dopamine enhances motor and neuropathological consequences of polyglutamine expanded huntingtin.	Dopamine	0-8	huntingtin	Mus musculus	85-95	
17065224-1	2006	An expansion in the CAG repeat of the IT15 (huntingtin) gene underlies the development of Huntington"s disease (HD), but the basis for the specific vulnerability of dopamine-receptive striatal neurons remains unclear.	Dopamine	165-173	huntingtin	Mus musculus	38-42	
17065224-1	2006	An expansion in the CAG repeat of the IT15 (huntingtin) gene underlies the development of Huntington"s disease (HD), but the basis for the specific vulnerability of dopamine-receptive striatal neurons remains unclear.	Dopamine	165-173	huntingtin	Mus musculus	44-54	
17065224-8	2006	These findings indicate that dopamine contributes to the deleterious effects of mutated huntingtin on striatal function, and this is accompanied by enhanced formation of huntingtin aggregates.	Dopamine	29-37	huntingtin	Mus musculus	88-98	
17065224-8	2006	These findings indicate that dopamine contributes to the deleterious effects of mutated huntingtin on striatal function, and this is accompanied by enhanced formation of huntingtin aggregates.	Dopamine	29-37	huntingtin	Mus musculus	170-180	
16103364-5	2005	Using primary cultures of striatal neurons transiently expressing GFP-tagged-exon 1 of mutated huntingtin, we show that low doses of DA (100 microM) act synergistically with mutated huntingtin to activate the proapoptotic transcription factor c-Jun.	Dopamine	133-135	huntingtin	Mus musculus	95-105	
16103364-5	2005	Using primary cultures of striatal neurons transiently expressing GFP-tagged-exon 1 of mutated huntingtin, we show that low doses of DA (100 microM) act synergistically with mutated huntingtin to activate the proapoptotic transcription factor c-Jun.	Dopamine	133-135	huntingtin	Mus musculus	182-192	
16103364-6	2005	Surprisingly, DA also increases aggregate formation of mutated huntingtin in all cellular compartments, including neurites, soma, and nuclei.	Dopamine	14-16	huntingtin	Mus musculus	63-73	
16103364-10	2005	Blocking ROS production, JNK activation, or D2 receptor stimulation significantly reversed DA aggravation of mutated huntingtin-induced striatal death.	Dopamine	91-93	huntingtin	Mus musculus	117-127	
16103364-11	2005	The combined treatment with the ROS scavenger and D2 antagonist totally reversed DA"s effects on mutated huntingtin-induced striatal death.	Dopamine	81-83	huntingtin	Mus musculus	105-115