PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25656918-3 2015 The results from single point time dependent inhibition and shift assays suggest that clorgyline, pargyline, phenelzine, and selegiline were metabolism based inhibitors of CYP2B6. Phenelzine 109-119 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 172-178 25656918-4 2015 In IC50 shift assays, clorgyline, pargyline, phenelzine and selegiline are metabolism based inhibitors of CYP2B6 with fold shit of 3.0-, 3.7-, 2.9-, and 11.4-fold respectively. Phenelzine 45-55 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 106-112 25656918-6 2015 Phenelzine inactivated CYP2B6 with KI and k(inact) values of 44.9 +- 6.9 muM and 0.085 +- 0.003 min(-1) respectively. Phenelzine 0-10 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 23-29 25656918-13 2015 Caution is required while co-administering phenelzine with substrates that are exclusively metabolized by CYP2B6 enzyme and substrates that have narrow therapeutic index. Phenelzine 43-53 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 106-112