PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23151889-6 2013 Furthermore, surfactin strongly repressed the TPA-induced phosphorylation of Akt and extracellular signal-regulated kinase (ERK). surfactin peptide 13-22 mitogen-activated protein kinase 1 Homo sapiens 97-134 23733672-0 2013 Surfactin-induced apoptosis through ROS-ERS-Ca2+-ERK pathways in HepG2 cells. surfactin peptide 0-9 mitogen-activated protein kinase 1 Homo sapiens 49-52 23733672-7 2013 According to a comprehensive review of all the evidence, it is concluded that surfactin induces apoptosis of HepG2 cells through a ROS-ERS-Ca(2+) mediated ERK pathway. surfactin peptide 78-87 mitogen-activated protein kinase 1 Homo sapiens 155-158 23151889-6 2013 Furthermore, surfactin strongly repressed the TPA-induced phosphorylation of Akt and extracellular signal-regulated kinase (ERK). surfactin peptide 13-22 mitogen-activated protein kinase 1 Homo sapiens 136-139 23151889-8 2013 These results suggest that the surfactin-mediated inhibition of breast cancer cell invasion and MMP-9 expression involves the suppression of the NF-kappaB, AP-1, phosphatidylinositol 3-kinase (PI-3K)/Akt and the ERK signaling pathways. surfactin peptide 43-52 mitogen-activated protein kinase 1 Homo sapiens 248-251