PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23906708-2	2013	In this study, we investigated the effects of surfactin, a surfactant from Bacillus subtilis, on oligomeric amyloid beta (Abeta)-induced microglial activation and neurotoxicity.	surfactin peptide	46-55	amyloid beta (A4) precursor protein	Mus musculus	122-127	
23906708-3	2013	Surfactin significantly suppressed expression of MMP-9, iNOS and COX-2, as well as production of ROS, NO, PGE2, TNF-alpha, IL-1beta, IL-6 and MCP-1 in Abeta-stimulated BV-2 microglial cells.	surfactin peptide	0-9	amyloid beta (A4) precursor protein	Mus musculus	151-156	
23906708-4	2013	Moreover, surfactin markedly inhibited Abeta-induced nuclear translocation and activation of NF-kappaB as well as phosphorylation of JNK and p38 MAPK.	surfactin peptide	10-19	amyloid beta (A4) precursor protein	Mus musculus	39-44	
23906708-5	2013	Furthermore, surfactin protected hippocampal HT22 cells from indirect neuronal toxicity mediated by Abeta-treated microglial cells, but had no effect on Abeta-induced direct toxicity to HT22 cells.	surfactin peptide	13-22	amyloid beta (A4) precursor protein	Mus musculus	100-105	
23906708-6	2013	These results suggest that surfactin impairs the Abeta-induced inflammatory response of microglial cells and confers protection against indirect neurotoxicity to hippocampal cells.	surfactin peptide	27-36	amyloid beta (A4) precursor protein	Mus musculus	49-54