PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1904620-2 1991 Moclobemide belongs to a new class of substances called RIMA (Reversible Inhibitor of the monoamine oxidase type A). rima 56-60 monoamine oxidase A Homo sapiens 90-114 1347658-3 1992 A new class of RIMA (Reversible Inhibitors of MAO-A) represented by moclobemide requires a change in clinical thinking on antidepressants. rima 15-19 monoamine oxidase A Homo sapiens 46-51 1546143-1 1992 RIMA is a term for reversible inhibitors of monoamine oxidase (MAO) with preference for MAO-A; moclobemide is a prototype of this new class of antidepressants and is a highly selective inhibitor of MAO-A in vitro. rima 0-4 monoamine oxidase A Homo sapiens 88-93 1546143-1 1992 RIMA is a term for reversible inhibitors of monoamine oxidase (MAO) with preference for MAO-A; moclobemide is a prototype of this new class of antidepressants and is a highly selective inhibitor of MAO-A in vitro. rima 0-4 monoamine oxidase A Homo sapiens 198-203 7905288-1 1993 Moclobemide, p-chloro-N-[morpholinoethyl]benzamide, is a prototype of RIMA (reversible inhibitor of MAO-A) agents. rima 70-74 monoamine oxidase A Homo sapiens 100-105 14697899-6 2004 The consequence of these findings were the development of reversible MAO-A inhibitors (RIMA), moclobemide and brofaromin, as antidepressants and possible anti-Parkinson activity, with limited tyramine potentiation, since the amine can displace the inhibitor from its binding site on the enzyme. rima 87-91 monoamine oxidase A Homo sapiens 69-74 19890267-8 2010 Thus, CX157 is the first agent in the RIMA class with documented reversible inhibition of human brain MAO-A, supporting its classification as a RIMA, and the first RIMA with observed plasma levels that can serve as a biomarker for the degree of brain MAO-A inhibition. rima 38-42 monoamine oxidase A Homo sapiens 102-107 2123366-1 1990 Moclobemide, a new selective and reversible inhibitor of monoamine oxidase A (RIMA), has been compared with various tricyclic antidepressants (TCAs) in numerous controlled studies. rima 78-82 monoamine oxidase A Homo sapiens 57-76 32403270-3 2020 In this work, we aimed to find potential drugs for PCa patients suffering from depression by establishing novel anti-PCa reversible monoamine oxidase-A inhibitors (MAO-AIs/RIMA); with an endeavor to understand their mechanism of action. rima 172-176 monoamine oxidase A Homo sapiens 132-151 10410765-1 1999 Moclobemide, the first reversible inhibitor of MAOA (so-called RIMA) to become widely available for clinical use, is an effective and well-tolerated antidepressant. rima 63-67 monoamine oxidase A Homo sapiens 47-51 11294480-2 2001 This study examines the relation between baseline clinical characteristics in patients with posttraumatic stress disorder (PTSD) and response to treatment with a reversible monoamine oxidase A inhibitor (RIMA), brofaromine. rima 204-208 monoamine oxidase A Homo sapiens 173-192 9273760-2 1997 Moclobemide is a reversible inhibitor of the monoamine oxidase type A (RIMA). rima 71-75 monoamine oxidase A Homo sapiens 45-69