PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30772266-0	2019	The role of the Hint1 protein in the metabolism of phosphorothioate oligonucleotides drugs and prodrugs, and the release of H2S under cellular conditions.	Deuterium	124-127	histidine triad nucleotide binding protein 1	Homo sapiens	16-21	
30772266-4	2019	We previously found that (d)NMPS were desulfurated in vitro to yield (d)NMP and H2S in a Hint1-assisted reaction.	Deuterium	80-83	histidine triad nucleotide binding protein 1	Homo sapiens	89-94	
30772266-9	2019	These results suggest that the metabolic pathway of PS-oligos includes hydrolysis into (d)NMPS (by cellular nucleases) followed by Hint1-promoted conversion of the resulting (d)NMPS into (d)NMP accompanied by H2S elimination.	Deuterium	209-212	histidine triad nucleotide binding protein 1	Homo sapiens	131-136