PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8259552-6 1993 Both t-PA and PAI-1 were associated positively with body mass index and blood triglycerides for all sex-race groups, and positively with alcohol intake for Japanese and Caucasian men. Alcohols 137-144 chromosome 20 open reading frame 181 Homo sapiens 5-9 9607117-6 1998 The ratio, tPA/PAI-1, fell from 0.50 to 0.44 (P = 0.02) confirming the relatively greater increase in PAI-1 with alcohol consumption. Alcohols 113-120 chromosome 20 open reading frame 181 Homo sapiens 11-14 9607117-9 1998 The increase in factor VII and relatively greater increase in PAI-1 than tPA with alcohol intake may attenuate this benefit and indeed may sufficiently predispose individuals to thrombosis to contribute to the increased incidence of ischaemic stroke seen in heavier drinkers. Alcohols 82-89 chromosome 20 open reading frame 181 Homo sapiens 73-76 19715411-4 2009 Alcohol affects several biochemical factors that have potential cardioprotective benefits, including lipids, platelet aggregation, fibrinogen, tissue-plasminogen activator, plasminogen-activator inhibitor and omega-3 fatty acids. Alcohols 0-7 chromosome 20 open reading frame 181 Homo sapiens 143-171 24117907-8 2014 These novel studies show that ethanol inhibits DNA methylation in astrocytes leading to increased tPA expression and release; this effect may be involved in astrocyte-mediated inhibition of neuronal plasticity by alcohol. Alcohols 213-220 chromosome 20 open reading frame 181 Homo sapiens 98-101 14972427-4 2004 Tissue plasminogen activator antigen values were strongly correlated with several vascular risk factors, including serum lipids, body mass index, alcohol consumption, and markers of systemic inflammation. Alcohols 146-153 chromosome 20 open reading frame 181 Homo sapiens 0-28