PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11179732-7 2001 The preferred conformations, inferred from an analysis of (13)C-NMR characteristics, notably the chemical shift of C-17 in a series of analogs, to have the tertiary alcohol (1"-hydroxy-1"-methylethyl) substituent equatorial on the cyclohexane chair, are confirmed by molecular modeling. Alcohols 165-172 cytokine like 1 Homo sapiens 115-119 22613542-0 2012 ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior. Alcohols 42-49 cytokine like 1 Homo sapiens 11-16 22613542-9 2012 The association of alcohol consumption was successfully replicated with rs4295599 in ANKRD7 gene in independent Caucasian nuclear families and independent unrelated Chinese Hans, and with rs16836497 in CYTL1 gene in independent unrelated Caucasians. Alcohols 19-26 cytokine like 1 Homo sapiens 202-207 22613542-10 2012 Meta-analyses based on both the GWAS and replication samples further supported the observed significant associations between the ANKRD7 or CYTL1 gene and alcohol consumption. Alcohols 154-161 cytokine like 1 Homo sapiens 139-144 1504919-4 1992 Amino acid sequence analyses show that human 17 beta-hydroxysteroid dehydrogenase, which catalyzes the interconversion of the alcohol and ketone at C17 on estrogens and androgens, and rat 11 beta-hydroxysteroid dehydrogenase, which catalyzes the interconversion of the alcohol and ketone at C11 of glucocorticoids, and Rhizobium meliloti NodG and Bradyrhizobium japonicum. Alcohols 126-133 cytokine like 1 Homo sapiens 148-151 1504919-4 1992 Amino acid sequence analyses show that human 17 beta-hydroxysteroid dehydrogenase, which catalyzes the interconversion of the alcohol and ketone at C17 on estrogens and androgens, and rat 11 beta-hydroxysteroid dehydrogenase, which catalyzes the interconversion of the alcohol and ketone at C11 of glucocorticoids, and Rhizobium meliloti NodG and Bradyrhizobium japonicum. Alcohols 269-276 cytokine like 1 Homo sapiens 148-151 24285238-2 2013 Although we could not selectively protect the C17 alcohol in the presence of the C16 alcohol, we were able to prepare and chromatographically isolate the desired C16 TBDMS, C17,C3-dimethoxymethyl (diMOM) protected estriol derivative and convert into the ultimate fluorination precursor. Alcohols 85-92 cytokine like 1 Homo sapiens 173-195 970695-4 1976 It catalyses the transformation into ketone of the secondary alcohol group at the 3 beta position of sterols which possess in the C17 position a lateral chain of at least two carbon atoms. Alcohols 61-68 cytokine like 1 Homo sapiens 130-133 31089746-7 2019 More recently, studies have also potentially linked Cytl1 with a variety of conditions including cardiac fibrosis, smoking, alcohol dependence risk, and tumours such as benign prostatic hypertrophy, lung squamous cell carcinoma, neuroblastoma and familial colorectal cancer. Alcohols 124-131 cytokine like 1 Homo sapiens 52-57 24285238-4 2013 The di-MOM protective precursor at the C3 and C17 alcohols instead of a cyclic sulfate group shortened hydrolysis time. Alcohols 50-58 cytokine like 1 Homo sapiens 46-49 23344201-3 2013 After the protection of the alcohol at C3, the C17-ketone was alkylated with the lithium acetylide of tetrahydro-2-(but-3-ynyl)-2-H-pyran, the triple bond was hydrogenated, the protecting groups hydrolysed and the alcohols oxidized to give the corresponding 3-keto-17-spiro-lactone derivative. Alcohols 28-35 cytokine like 1 Homo sapiens 47-50 23344201-3 2013 After the protection of the alcohol at C3, the C17-ketone was alkylated with the lithium acetylide of tetrahydro-2-(but-3-ynyl)-2-H-pyran, the triple bond was hydrogenated, the protecting groups hydrolysed and the alcohols oxidized to give the corresponding 3-keto-17-spiro-lactone derivative. Alcohols 214-222 cytokine like 1 Homo sapiens 47-50