PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32199616-2 2020 Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers. ses 83-86 bromodomain containing 4 Homo sapiens 52-56 29930091-2 2018 Here we demonstrate that the SE-enriched transcriptional coactivators BRD4 and MED1 form nuclear puncta at SEs that exhibit properties of liquid-like condensates and are disrupted by chemicals that perturb condensates. ses 107-110 bromodomain containing 4 Homo sapiens 70-74 27425608-5 2016 A miR-9 mimic represses stimulus-dependent targeting of BRD4 to SEs and blunts Pol II phosphorylation at proximal transcription start sites, without affecting BRD4 binding to SEs that control constitutively expressed cardiac genes. ses 64-67 bromodomain containing 4 Homo sapiens 56-60 30466442-2 2018 Inhibition of BRD4 shortcuts the communication between SEs and target promoters with a subsequent cell-specific repression of oncogenes to which cancer cells are addicted and cell death. ses 55-58 bromodomain containing 4 Homo sapiens 14-18 26546038-4 2015 Previously, SEs have been defined as having the highest density of Med1, Brd4 or H3K27ac by ChIP-seq. ses 12-15 bromodomain containing 4 Homo sapiens 73-77