PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12582005-10 2003 The cytochrome P-450 epoxyeicosatrienoic acid (EET) metabolite 14,15-EET (5 x 10(-7) M) inhibited both apical and basolateral cotransport, whereas 8,9-EET and 11,12-EET had no significant effect. 14,15-epoxy-5,8,11-eicosatrienoic acid 63-72 cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus 4-20 30429460-3 2018 Here, we found 14,15-epoxyeicosatrienoic acid (14,15-EET), a cytochrome P450 (CYP) metabolite, from hUCB-MSCs and the cerebella of NPC1-mutant mice and investigated the functional consequence of this metabolite. 14,15-epoxy-5,8,11-eicosatrienoic acid 15-45 cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus 61-76 30429460-3 2018 Here, we found 14,15-epoxyeicosatrienoic acid (14,15-EET), a cytochrome P450 (CYP) metabolite, from hUCB-MSCs and the cerebella of NPC1-mutant mice and investigated the functional consequence of this metabolite. 14,15-epoxy-5,8,11-eicosatrienoic acid 15-45 cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus 78-81 30429460-3 2018 Here, we found 14,15-epoxyeicosatrienoic acid (14,15-EET), a cytochrome P450 (CYP) metabolite, from hUCB-MSCs and the cerebella of NPC1-mutant mice and investigated the functional consequence of this metabolite. 14,15-epoxy-5,8,11-eicosatrienoic acid 47-56 cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus 61-76 30429460-3 2018 Here, we found 14,15-epoxyeicosatrienoic acid (14,15-EET), a cytochrome P450 (CYP) metabolite, from hUCB-MSCs and the cerebella of NPC1-mutant mice and investigated the functional consequence of this metabolite. 14,15-epoxy-5,8,11-eicosatrienoic acid 47-56 cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus 78-81 30429460-6 2018 In this regard, we found that one CYP metabolite, 14,15-EET, acts as a key mediator in ameliorating cholesterol accumulation. 14,15-epoxy-5,8,11-eicosatrienoic acid 50-59 cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus 34-37 30429460-8 2018 We show that the reduced activity within the CYP system in the cerebellum could cause the neurological symptoms of NPC1 patients, as 14,15-EET treatment significantly rescued cholesterol accumulation and impaired autophagy. 14,15-epoxy-5,8,11-eicosatrienoic acid 133-142 cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus 45-48