PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16617161-8	2006	A three-dimensional model of CYP24A1 indicated that the A-ring and triene part of 1alpha,25(OH)2D3 could be located close to amino acid residues at positions 416 and 500, respectively.	25(oh)2d3	89-98	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	29-36	
19667160-1	2009	Tissue-specific expression of 25-hydroxyvitamin D-1alpha-hydroxylase (1alpha-OHase) and vitamin D-hydroxylase (24-OHase) may act as the pivotal link between 25-hydroxyvitamin D3 (25(OH)D3) serum levels and the anticancer effects of 1,25-dihydoxyvitamin D3 (1,25(OH)2D3) and alternative splicing of the enzymes may regulate their biological function.	25(oh)2d3	259-268	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	111-119	
24291609-4	2014	The effects of the cell-derived 1alpha,25(OH)2D3 on vitamin D3 24-hydroxylase (CYP24A1) mRNA level and the cell growth inhibition were significantly lower than the effects of 25(OH)D3 itself added to cell culture.	25(oh)2d3	39-48	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	79-86	
34534339-4	2021	Uptake of 25(OH)D3 led to a significant upregulation of vitamin D metabolizing CYP24A1 mRNA levels, indicating that kidney organoids possess a feedback mechanism to control active vitamin D (1,25(OH)2D3) levels.	25(oh)2d3	193-202	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	79-86	
15574355-9	2005	CYP24A1 expressed in E. coli showed a remarkable metabolic processes of 25(OH)D3 and 1alpha,25(OH)2D3.	25(oh)2d3	92-101	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	0-7	
15488475-6	2004	Production of the metabolites including the 25-hydroxylated ones was detectable only when CYP24A1 activity was induced in keratinocytes 1alpha,25(OH)2D3.	25(oh)2d3	143-152	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	90-97	
34593422-6	2021	The inhibitory effect of 25(OH)D3 on cell proliferation was potentiated after inhibition of CYP17B1 and CYP24 by genistein, preventing further metabolism of 25(OH)D3 to 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) and 24,25-dihydroxyvitamin D3 (24,25(OH)2D3).	25(oh)2d3	242-251	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	104-109	
34980721-1	2021	CYP24A1 regulates serum vitamin D (VD) levels by inactivating 25(OH)2D3, which is the precursor of the active form of VD (1alpha,25(OH)2D3), and CYP24A1 expression is controlled by multiple calcemic factors such as 1alpha,25(OH)2D3, calcium, and phosphate.	25(oh)2d3	62-71	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	0-7	
34980721-1	2021	CYP24A1 regulates serum vitamin D (VD) levels by inactivating 25(OH)2D3, which is the precursor of the active form of VD (1alpha,25(OH)2D3), and CYP24A1 expression is controlled by multiple calcemic factors such as 1alpha,25(OH)2D3, calcium, and phosphate.	25(oh)2d3	129-138	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	0-7	
34980721-1	2021	CYP24A1 regulates serum vitamin D (VD) levels by inactivating 25(OH)2D3, which is the precursor of the active form of VD (1alpha,25(OH)2D3), and CYP24A1 expression is controlled by multiple calcemic factors such as 1alpha,25(OH)2D3, calcium, and phosphate.	25(oh)2d3	222-231	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	0-7	
34980721-1	2021	CYP24A1 regulates serum vitamin D (VD) levels by inactivating 25(OH)2D3, which is the precursor of the active form of VD (1alpha,25(OH)2D3), and CYP24A1 expression is controlled by multiple calcemic factors such as 1alpha,25(OH)2D3, calcium, and phosphate.	25(oh)2d3	222-231	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	145-152	
24291609-4	2014	The effects of the cell-derived 1alpha,25(OH)2D3 on vitamin D3 24-hydroxylase (CYP24A1) mRNA level and the cell growth inhibition were significantly lower than the effects of 25(OH)D3 itself added to cell culture.	25(oh)2d3	39-48	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	52-77	
23869778-1	2014	The expression of CYP27B1 or vitamin D 1alpha-hydroxylase (1alpha-OHase) and CYP24A1 in specific tissues may act as the central part between 25-hydroxyvitamin D [25(OH)D] serum levels and the anticancer effects of1alpha,25-dihydroxyvitamin D [1alpha,25(OH)2D3],alternative splicing of these enzymes may affect their biological functions.	25(oh)2d3	250-259	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	77-84	
23059474-6	2013	The over expression of CYP24A1 in cancer cells may be a factor affecting 1,25(OH)2D3 bioavailability and anti-proliferative activity pre-clinically and clinically.	25(oh)2d3	75-84	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	23-30	
20619365-8	2011	1alpha,25(OH)2D3 levels are short-lived: the hormone upregulates its rapid metabolism by CYP24A1 that attacks repeatedly the vitamin D C20-27 side chain, thereby producing a complex cascade of transient metabolites with increasing polarity.	25(oh)2d3	7-16	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	89-96	
20307664-5	2010	VDR mRNA expression was detected in all samples and CYP24A1 mRNA expression was induced by 1alpha,25(OH)2D3 in both concentrations (but mainly with 100 nM).	25(oh)2d3	98-107	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	52-59