PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24291609-4 2014 The effects of the cell-derived 1alpha,25(OH)2D3 on vitamin D3 24-hydroxylase (CYP24A1) mRNA level and the cell growth inhibition were significantly lower than the effects of 25(OH)D3 itself added to cell culture. 25(oh)2d3 39-48 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 79-86 24291609-4 2014 The effects of the cell-derived 1alpha,25(OH)2D3 on vitamin D3 24-hydroxylase (CYP24A1) mRNA level and the cell growth inhibition were significantly lower than the effects of 25(OH)D3 itself added to cell culture. 25(oh)2d3 39-48 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 52-77 23869778-1 2014 The expression of CYP27B1 or vitamin D 1alpha-hydroxylase (1alpha-OHase) and CYP24A1 in specific tissues may act as the central part between 25-hydroxyvitamin D [25(OH)D] serum levels and the anticancer effects of1alpha,25-dihydroxyvitamin D [1alpha,25(OH)2D3],alternative splicing of these enzymes may affect their biological functions. 25(oh)2d3 250-259 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 77-84 19667160-1 2009 Tissue-specific expression of 25-hydroxyvitamin D-1alpha-hydroxylase (1alpha-OHase) and vitamin D-hydroxylase (24-OHase) may act as the pivotal link between 25-hydroxyvitamin D3 (25(OH)D3) serum levels and the anticancer effects of 1,25-dihydoxyvitamin D3 (1,25(OH)2D3) and alternative splicing of the enzymes may regulate their biological function. 25(oh)2d3 259-268 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 111-119 23059474-6 2013 The over expression of CYP24A1 in cancer cells may be a factor affecting 1,25(OH)2D3 bioavailability and anti-proliferative activity pre-clinically and clinically. 25(oh)2d3 75-84 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 23-30 20619365-8 2011 1alpha,25(OH)2D3 levels are short-lived: the hormone upregulates its rapid metabolism by CYP24A1 that attacks repeatedly the vitamin D C20-27 side chain, thereby producing a complex cascade of transient metabolites with increasing polarity. 25(oh)2d3 7-16 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 89-96 20307664-5 2010 VDR mRNA expression was detected in all samples and CYP24A1 mRNA expression was induced by 1alpha,25(OH)2D3 in both concentrations (but mainly with 100 nM). 25(oh)2d3 98-107 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 52-59 15574355-9 2005 CYP24A1 expressed in E. coli showed a remarkable metabolic processes of 25(OH)D3 and 1alpha,25(OH)2D3. 25(oh)2d3 92-101 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 0-7 16617161-8 2006 A three-dimensional model of CYP24A1 indicated that the A-ring and triene part of 1alpha,25(OH)2D3 could be located close to amino acid residues at positions 416 and 500, respectively. 25(oh)2d3 89-98 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 29-36 15488475-6 2004 Production of the metabolites including the 25-hydroxylated ones was detectable only when CYP24A1 activity was induced in keratinocytes 1alpha,25(OH)2D3. 25(oh)2d3 143-152 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 90-97 34534339-4 2021 Uptake of 25(OH)D3 led to a significant upregulation of vitamin D metabolizing CYP24A1 mRNA levels, indicating that kidney organoids possess a feedback mechanism to control active vitamin D (1,25(OH)2D3) levels. 25(oh)2d3 193-202 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 79-86 34593422-6 2021 The inhibitory effect of 25(OH)D3 on cell proliferation was potentiated after inhibition of CYP17B1 and CYP24 by genistein, preventing further metabolism of 25(OH)D3 to 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) and 24,25-dihydroxyvitamin D3 (24,25(OH)2D3). 25(oh)2d3 242-251 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 104-109 34980721-1 2021 CYP24A1 regulates serum vitamin D (VD) levels by inactivating 25(OH)2D3, which is the precursor of the active form of VD (1alpha,25(OH)2D3), and CYP24A1 expression is controlled by multiple calcemic factors such as 1alpha,25(OH)2D3, calcium, and phosphate. 25(oh)2d3 62-71 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 0-7 34980721-1 2021 CYP24A1 regulates serum vitamin D (VD) levels by inactivating 25(OH)2D3, which is the precursor of the active form of VD (1alpha,25(OH)2D3), and CYP24A1 expression is controlled by multiple calcemic factors such as 1alpha,25(OH)2D3, calcium, and phosphate. 25(oh)2d3 129-138 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 0-7 34980721-1 2021 CYP24A1 regulates serum vitamin D (VD) levels by inactivating 25(OH)2D3, which is the precursor of the active form of VD (1alpha,25(OH)2D3), and CYP24A1 expression is controlled by multiple calcemic factors such as 1alpha,25(OH)2D3, calcium, and phosphate. 25(oh)2d3 222-231 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 0-7 34980721-1 2021 CYP24A1 regulates serum vitamin D (VD) levels by inactivating 25(OH)2D3, which is the precursor of the active form of VD (1alpha,25(OH)2D3), and CYP24A1 expression is controlled by multiple calcemic factors such as 1alpha,25(OH)2D3, calcium, and phosphate. 25(oh)2d3 222-231 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 145-152