PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24760553-7 2014 The approach used to analyze genetic association with the SAM/SAH metabolites is called middle-out: SNPs in 275 genes involved in the one-carbon pathway (folate, pyridoxal/pyridoxine, thiamin) or were correlated with SAM/SAH (vitamin A, E, Hcy) were analyzed instead of the entire 1M SNP data set. Pyridoxal 162-171 acyl-CoA synthetase medium chain family member 3 Homo sapiens 58-65