PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31717501-6	2019	Based on this finding, we propose that hCES1 substrates with beta-aminocarboxylester structure might form orthoester intermediates in hCES1-catalyzed hydrolysis, and therefore prolong their in vivo half-life.	5alpha-pregnane-3beta,11beta,20beta,21-tetrol	61-84	carboxylesterase 1	Homo sapiens	39-44	
31717501-6	2019	Based on this finding, we propose that hCES1 substrates with beta-aminocarboxylester structure might form orthoester intermediates in hCES1-catalyzed hydrolysis, and therefore prolong their in vivo half-life.	5alpha-pregnane-3beta,11beta,20beta,21-tetrol	61-84	carboxylesterase 1	Homo sapiens	134-139