PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11041253-2 2000 Moreover, we indicated that 72-kDa stress protein (Hsp72) was induced in cultured human pulmonary (L-132) cells by exposure to DMA and was accumulated specifically in the cell nuclei. Cacodylic Acid 127-130 heat shock protein family A (Hsp70) member 1A Homo sapiens 51-56 10598025-0 1999 Dimethylarsinic acid exposure causes accumulation of Hsp72 in cell nuclei and suppresses apoptosis in human alveolar cultured (L-132) cells. Cacodylic Acid 0-20 heat shock protein family A (Hsp70) member 1A Homo sapiens 53-58 10598025-1 1999 We previously found that 72-kDa heat shock protein (Hsp72) was induced and accumulated in the nuclei, together with DNA damage, in human alveolar epithelial (L-132) cells by exposure to dimethylarsinic acid (DMAA), which is a main metabolite of inorganic arsenics in mammals. Cacodylic Acid 186-206 heat shock protein family A (Hsp70) member 1A Homo sapiens 52-57 10598025-1 1999 We previously found that 72-kDa heat shock protein (Hsp72) was induced and accumulated in the nuclei, together with DNA damage, in human alveolar epithelial (L-132) cells by exposure to dimethylarsinic acid (DMAA), which is a main metabolite of inorganic arsenics in mammals. Cacodylic Acid 208-212 heat shock protein family A (Hsp70) member 1A Homo sapiens 52-57 10598025-2 1999 In the present study, the intracellular behavior of Hsp72 was investigated during the recovery from the DNA damage induced by exposure to DMAA. Cacodylic Acid 138-142 heat shock protein family A (Hsp70) member 1A Homo sapiens 52-57 10598025-4 1999 The induction of Hsp72 by exposure to DMAA reached a peak at 6-9 h after removal of DMAA. Cacodylic Acid 38-42 heat shock protein family A (Hsp70) member 1A Homo sapiens 17-22 10598025-4 1999 The induction of Hsp72 by exposure to DMAA reached a peak at 6-9 h after removal of DMAA. Cacodylic Acid 84-88 heat shock protein family A (Hsp70) member 1A Homo sapiens 17-22 10598025-5 1999 However, the cell-nuclear distribution of Hsp72 was observed until 3 h after the start of DMAA-free incubation. Cacodylic Acid 90-94 heat shock protein family A (Hsp70) member 1A Homo sapiens 42-47 9145211-1 1997 The induction and subsequent intracellular distribution of the 72-kDa heat shock (stress) protein (Hsp72) by exposure of cultured human alveolar (L-132) cells to dimethylarsinic acid (DMAA), a main metabolite of inorganic arsenics in mammals, were examined. Cacodylic Acid 162-182 heat shock protein family A (Hsp70) member 1A Homo sapiens 99-104 9145211-2 1997 A significant induction of Hsp72 in the cells was observed by exposure to 10mM DMAA for 6 h. The induction was similar to the case by arsenite for 6 h or by heat treatment at 42 degrees C for 3h. Cacodylic Acid 79-83 heat shock protein family A (Hsp70) member 1A Homo sapiens 27-32 9145211-3 1997 However, the nuclear distribution of Hsp72 differed greatly between DMAA and 42 degrees C treatment or arsenite exposure, i.e., Hsp72 induced by exposure to DMAA accumulated not only in the nucleoli but also in the nucleoplasm, whereas that by 42 degrees C or arsenite exposure did not accumulate in the nucleoplasm. Cacodylic Acid 68-72 heat shock protein family A (Hsp70) member 1A Homo sapiens 37-42 9145211-3 1997 However, the nuclear distribution of Hsp72 differed greatly between DMAA and 42 degrees C treatment or arsenite exposure, i.e., Hsp72 induced by exposure to DMAA accumulated not only in the nucleoli but also in the nucleoplasm, whereas that by 42 degrees C or arsenite exposure did not accumulate in the nucleoplasm. Cacodylic Acid 68-72 heat shock protein family A (Hsp70) member 1A Homo sapiens 128-133 9145211-3 1997 However, the nuclear distribution of Hsp72 differed greatly between DMAA and 42 degrees C treatment or arsenite exposure, i.e., Hsp72 induced by exposure to DMAA accumulated not only in the nucleoli but also in the nucleoplasm, whereas that by 42 degrees C or arsenite exposure did not accumulate in the nucleoplasm. Cacodylic Acid 157-161 heat shock protein family A (Hsp70) member 1A Homo sapiens 37-42 9145211-3 1997 However, the nuclear distribution of Hsp72 differed greatly between DMAA and 42 degrees C treatment or arsenite exposure, i.e., Hsp72 induced by exposure to DMAA accumulated not only in the nucleoli but also in the nucleoplasm, whereas that by 42 degrees C or arsenite exposure did not accumulate in the nucleoplasm. Cacodylic Acid 157-161 heat shock protein family A (Hsp70) member 1A Homo sapiens 128-133 9145211-4 1997 Furthermore, the Hsp72 accumulated in the nucleus by DMAA exposure hardly diffused with the addition of ATP, suggesting that the DMAA-induced Hsp72 strongly binds to some macromolecules in the nucleus. Cacodylic Acid 53-57 heat shock protein family A (Hsp70) member 1A Homo sapiens 17-22 9145211-4 1997 Furthermore, the Hsp72 accumulated in the nucleus by DMAA exposure hardly diffused with the addition of ATP, suggesting that the DMAA-induced Hsp72 strongly binds to some macromolecules in the nucleus. Cacodylic Acid 53-57 heat shock protein family A (Hsp70) member 1A Homo sapiens 142-147 9145211-4 1997 Furthermore, the Hsp72 accumulated in the nucleus by DMAA exposure hardly diffused with the addition of ATP, suggesting that the DMAA-induced Hsp72 strongly binds to some macromolecules in the nucleus. Cacodylic Acid 129-133 heat shock protein family A (Hsp70) member 1A Homo sapiens 17-22 9145211-4 1997 Furthermore, the Hsp72 accumulated in the nucleus by DMAA exposure hardly diffused with the addition of ATP, suggesting that the DMAA-induced Hsp72 strongly binds to some macromolecules in the nucleus. Cacodylic Acid 129-133 heat shock protein family A (Hsp70) member 1A Homo sapiens 142-147 9145211-5 1997 The fact that Hsp72 induced by DMAA exposure accumulated in the nucleus of the cells may reflect a protective response toward the nucleus-specific damaging action of dimethylarsenics. Cacodylic Acid 31-35 heat shock protein family A (Hsp70) member 1A Homo sapiens 14-19