PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28153010-13	2017	In concert with these results, GO-203-induced suppression of TIGAR was associated with decreases in GSH levels.	(arginine)9-cysteinyl-glutaminyl-cysteinyl-arginyl-arginyl-lysyl-asparagine	31-37	TP53 induced glycolysis regulatory phosphatase	Homo sapiens	61-66	
28729399-6	2017	Present studies demonstrate that exposure of CTCL cells to decitabine in combination with GO-203, increased the generation of reactive oxygen species (ROS) levels and decreased levels of scavenger molecules, NADP, NADPH, glutathione, and TIGAR, critical to intracellular redox homeostasis.	(arginine)9-cysteinyl-glutaminyl-cysteinyl-arginyl-arginyl-lysyl-asparagine	90-96	TP53 induced glycolysis regulatory phosphatase	Homo sapiens	238-243	
28153010-11	2017	We show that GO-203-induced suppression of TIGAR is mediated by inhibition of AKT and the downstream mTOR pathway.	(arginine)9-cysteinyl-glutaminyl-cysteinyl-arginyl-arginyl-lysyl-asparagine	13-19	TP53 induced glycolysis regulatory phosphatase	Homo sapiens	43-48	
24632713-3	2014	The present results demonstrate that GO-203 and BTZ synergistically downregulate expression of the p53-inducible regulator of glycolysis and apoptosis (TIGAR), which promotes shunting of glucose-6-phosphate into the pentose phosphate pathway to generate reduced glutathione (GSH).	(arginine)9-cysteinyl-glutaminyl-cysteinyl-arginyl-arginyl-lysyl-asparagine	37-43	TP53 induced glycolysis regulatory phosphatase	Homo sapiens	152-157	
30523643-7	2019	We found that the inhibitory effect of GO-203 on TIGAR was mediated by inhibition of AKT-mTOR-S6K1 pathway.	(arginine)9-cysteinyl-glutaminyl-cysteinyl-arginyl-arginyl-lysyl-asparagine	39-45	TP53 induced glycolysis regulatory phosphatase	Homo sapiens	49-54	
30523643-8	2019	The findings also demonstrated that the suppressive effect of GO-203 on TIGAR is related to the decrease of glutathione level, the increase of reactive oxygen species and the loss of mitochondrial transmembrane membrane potential.	(arginine)9-cysteinyl-glutaminyl-cysteinyl-arginyl-arginyl-lysyl-asparagine	62-68	TP53 induced glycolysis regulatory phosphatase	Homo sapiens	72-77	
30523643-9	2019	In xenograft tissues, GO-203 inhibited the growth of ESCC cells and lead to the low expression of transmembrane C-terminal subunit (MUC1-C) and TIGAR.	(arginine)9-cysteinyl-glutaminyl-cysteinyl-arginyl-arginyl-lysyl-asparagine	22-28	TP53 induced glycolysis regulatory phosphatase	Homo sapiens	144-149