PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20122837-0 2010 Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) scaffold: exploration of P1" alkoxy residues and an aminoethylene (AE) central core. aziridine 128-141 beta-secretase 1 Homo sapiens 20-26 20122837-0 2010 Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) scaffold: exploration of P1" alkoxy residues and an aminoethylene (AE) central core. aziridine 143-145 beta-secretase 1 Homo sapiens 20-26 16451048-0 2006 Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1. aziridine 0-14 beta-secretase 1 Homo sapiens 104-110 16451048-1 2006 A series of novel beta-site amyloid precursor protein cleaving enzyme (BACE-1) inhibitors containing an aminoethylene (AE) tetrahedral intermediate isostere were synthesized and evaluated in comparison to corresponding hydroxyethylene (HE) compounds. aziridine 104-117 beta-secretase 1 Homo sapiens 71-77 16451048-1 2006 A series of novel beta-site amyloid precursor protein cleaving enzyme (BACE-1) inhibitors containing an aminoethylene (AE) tetrahedral intermediate isostere were synthesized and evaluated in comparison to corresponding hydroxyethylene (HE) compounds. aziridine 119-121 beta-secretase 1 Homo sapiens 71-77