PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2547872-3 1989 Consistent with this hypothesis, exposure of a plasma membrane rich preparation isolated from 32P labeled neutrophils to 20.0 mM NaF resulted in hydrolysis of labeled PIP2. Phosphatidylinositol 4,5-Diphosphate 167-171 C-X-C motif chemokine ligand 8 Homo sapiens 129-132 8027219-2 1994 We study here the regulation of the PiP2 cascade by TSH, ATP, NaF, and bradykinin. Phosphatidylinositol 4,5-Diphosphate 36-40 C-X-C motif chemokine ligand 8 Homo sapiens 62-65 8027219-4 1994 Activation of the PiP2 cascade by TSH (10 mU/mL), NaF, bradykinin, ionomycin, and 12-O-tetradecanoylphorbol-13-acetate stimulates iodide organification. Phosphatidylinositol 4,5-Diphosphate 18-22 C-X-C motif chemokine ligand 8 Homo sapiens 50-53 2547872-2 1989 Previous studies demonstrating hydrolysis of phosphatidylinositol bisphosphate (PIP2) and generation of inositol phosphates in neutrophils exposed to 20.0 mM NaF provide indirect evidence that activation of phospholipase-associated guanine nucleotide regulatory protein, a guanine nucleotide binding protein which regulates the activation of a membrane inositol-specific phospholipase C, is an early event in the neutrophil stimulus-response pathway triggered by fluoride. Phosphatidylinositol 4,5-Diphosphate 80-84 C-X-C motif chemokine ligand 8 Homo sapiens 158-161 2839752-5 1988 NaF plus AlCl3 induced increases in inositol tris-, bis-, and mono-phosphates and decreases in PtdIns(4,5)P2, phosphatidylinositol 4-phosphate, and phosphatidylinositol within 5 min after addition to the cytotoxin-treated cells at 37 C. GTP gamma S stimulated, to some extent, polyphosphoinositide hydrolysis in the cytotoxin-treated JURKAT. Phosphatidylinositol 4,5-Diphosphate 95-108 C-X-C motif chemokine ligand 8 Homo sapiens 0-3 3032933-3 1987 PtdIns-P2 phospholipase C was also activated by nucleoside triphosphates, citrate, EDTA, and NaF. Phosphatidylinositol 4,5-Diphosphate 0-9 C-X-C motif chemokine ligand 8 Homo sapiens 93-96 3015678-1 1986 Partially purified plasma membranes prepared from myo-[3H]inositol-prelabeled WRK1 cells exhibit a phosphatidylinositol 4,5-biphosphate (PIP2) phospholipase C activity sensitive to NaF. Phosphatidylinositol 4,5-Diphosphate 99-135 C-X-C motif chemokine ligand 8 Homo sapiens 181-184 3015678-1 1986 Partially purified plasma membranes prepared from myo-[3H]inositol-prelabeled WRK1 cells exhibit a phosphatidylinositol 4,5-biphosphate (PIP2) phospholipase C activity sensitive to NaF. Phosphatidylinositol 4,5-Diphosphate 137-141 C-X-C motif chemokine ligand 8 Homo sapiens 181-184