PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18614798-0 2008 Phosphatidylinositol (4,5)-bisphosphate modulates Nox5 localization via an N-terminal polybasic region. Phosphatidylinositol 4,5-Diphosphate 0-39 NADPH oxidase 5 Homo sapiens 50-54 18614798-2 2008 Here, we show that phosphatidylinositol (4,5)-bisphosphate [PtdIns(4,5)P(2)], a major phosphoinositide in plasma membrane, binds to human Nox5 causing Nox5 to localize from internal membranes to the plasma membrane. Phosphatidylinositol 4,5-Diphosphate 19-58 NADPH oxidase 5 Homo sapiens 138-142 18614798-2 2008 Here, we show that phosphatidylinositol (4,5)-bisphosphate [PtdIns(4,5)P(2)], a major phosphoinositide in plasma membrane, binds to human Nox5 causing Nox5 to localize from internal membranes to the plasma membrane. Phosphatidylinositol 4,5-Diphosphate 19-58 NADPH oxidase 5 Homo sapiens 151-155 18614798-4 2008 Mutations in PBR-N prevented PtdIns(4,5)P(2)-dependent localization of Nox5 to the plasma membrane and decreased extracellular ROS production. Phosphatidylinositol 4,5-Diphosphate 29-44 NADPH oxidase 5 Homo sapiens 71-75