PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25426030-1 2014 The trace amines (TAs), tryptamine, tyramine, and beta-phenylethylamine, are synthesized from precursor amino acids via aromatic-L-amino acid decarboxylase (AADC). phenethylamine 50-71 dopa decarboxylase Homo sapiens 120-155 7651438-6 1995 AADC also plays a controlling role in the central nervous system, being a regulatory enzyme in the synthesis of a putative neuromodulator 2-phenylethylamine and other trace amines. phenethylamine 138-156 dopa decarboxylase Homo sapiens 0-4 25426030-1 2014 The trace amines (TAs), tryptamine, tyramine, and beta-phenylethylamine, are synthesized from precursor amino acids via aromatic-L-amino acid decarboxylase (AADC). phenethylamine 50-71 dopa decarboxylase Homo sapiens 157-161 15900211-7 2005 These results demonstrate that the A1 allele of DRD2 gene is associated with increased striatal activity of aromatic L-amino acid decarboxylase, the final enzyme in the biosynthesis of dopamine and the rate-limiting enzyme for trace amine (e.g. beta-phenylethylamine) synthesis. phenethylamine 245-266 dopa decarboxylase Homo sapiens 108-143 10889538-2 2000 AADC does not catalyse the rate limiting step in either pathway, but is rate limiting in the synthesis of 2-phenylethylamine (2PE) which is a positive modulator of dopaminergic transmission and a candidate natural psychotogenic compound.1 We and others have proposed that polymorphism in AADC resulting in altered 2PE activity might contribute to the pathogenesis of psychosis. phenethylamine 106-124 dopa decarboxylase Homo sapiens 0-4 10889538-2 2000 AADC does not catalyse the rate limiting step in either pathway, but is rate limiting in the synthesis of 2-phenylethylamine (2PE) which is a positive modulator of dopaminergic transmission and a candidate natural psychotogenic compound.1 We and others have proposed that polymorphism in AADC resulting in altered 2PE activity might contribute to the pathogenesis of psychosis. phenethylamine 106-124 dopa decarboxylase Homo sapiens 288-292