PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28882785-9 2017 The expression of cyclin D1 and E was decreased and phosphorylation of CDK1 was increased by orlistat treatment in HSC-3 cells. Orlistat 93-101 cyclin D1 Homo sapiens 18-27 28882785-10 2017 Thus, orlistat induces apoptosis and cell cycle arrest in G2/M phase in HSC-3 cells through decrease in expression of cyclin D1 and E and increase in phosphorylation of CDK1. Orlistat 6-14 cyclin D1 Homo sapiens 118-127