PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7521133-3 1994 Intact IGFBP-3, as assessed by 125I-labeled IGF-II ligand blot analysis, is more abundant in culture media of cells exposed to growth hormone (GH) or to parathyroid hormone (PTH), both at 5 x 10(-9) mol/l, for 24 h. At the same time, concentrations of IGF-I are increased in media of cells exposed to PTH but not to GH, compared with hormone-free control cultures. Iodine-125 31-35 insulin-like growth factor 1 Rattus norvegicus 44-49 9688871-4 1998 Rats were treated with intravenous injections of 125I-labeled IGF-I, 125I-IGFBP-3, or 125I-IGFBP-4 alone or with complexes of 125I-IGF-I and IGFBP-3 or IGFBP-4. Iodine-125 49-53 insulin-like growth factor 1 Rattus norvegicus 62-67 7539476-9 1995 In the IGF-1-Tx group there was also increased iodine 125-labeled EGF binding and EGF-R protein. Iodine-125 47-57 insulin-like growth factor 1 Rattus norvegicus 7-12 7525251-2 1994 In the present studies, equimolar concentrations of equal specific activity 125I-labeled IGF-I, IGF-II, or insulin were infused into the carotid artery of anesthetized adult rats. Iodine-125 76-80 insulin-like growth factor 1 Rattus norvegicus 89-94 1431687-4 1992 Intracardial administration of Sprague-Dawley rats with 125I-labelled IGF-I and subsequent analysis of plasma and saliva samples by exclusion gel chromatography and SDS-PAGE, followed by autoradiography, demonstrated the apparent inability of IGF-I to cross from the plasma pool through to saliva. Iodine-125 56-60 insulin-like growth factor 1 Rattus norvegicus 70-75 2005410-1 1991 Incubation of 125I-labelled insulin-like growth factor-I (IGF-I) with rat plasma at 4 degrees C led to the transfer of approximately half the radioactivity to 150 kDa and smaller complexes with IGF-binding proteins. Iodine-125 14-18 insulin-like growth factor 1 Rattus norvegicus 28-56 1660511-3 1991 In membrane fractions prepared from either region, the binding of iodine 125-labeled IGF-I was demonstrated to be protein and temperature dependent, saturable, and specific. Iodine-125 66-76 insulin-like growth factor 1 Rattus norvegicus 85-90 1720805-1 1991 The purpose of this work was to study the effect of diabetes on 125I-labelled insulin-like growth factor (IGF) binding to specific serum binding proteins (IGFBPs) and the possible role of protein glycation in such an effect. Iodine-125 64-68 insulin-like growth factor 1 Rattus norvegicus 78-104 1720805-1 1991 The purpose of this work was to study the effect of diabetes on 125I-labelled insulin-like growth factor (IGF) binding to specific serum binding proteins (IGFBPs) and the possible role of protein glycation in such an effect. Iodine-125 64-68 insulin-like growth factor 1 Rattus norvegicus 106-109 1718411-4 1991 The binding capacity to plasma IGFBP of exogenously-added 125I-labelled insulin-like growth factor-1 (125I-IGF-1) was also studied. Iodine-125 58-62 insulin-like growth factor 1 Rattus norvegicus 107-112 1715379-5 1991 The binding of 125I-labelled IGF-I to IGFBPs from both control and SGA muscle was displaced equipotently by IGF-I and IGF-II and not at all by insulin. Iodine-125 15-19 insulin-like growth factor 1 Rattus norvegicus 29-34 1715379-5 1991 The binding of 125I-labelled IGF-I to IGFBPs from both control and SGA muscle was displaced equipotently by IGF-I and IGF-II and not at all by insulin. Iodine-125 15-19 insulin-like growth factor 1 Rattus norvegicus 108-113 2005410-1 1991 Incubation of 125I-labelled insulin-like growth factor-I (IGF-I) with rat plasma at 4 degrees C led to the transfer of approximately half the radioactivity to 150 kDa and smaller complexes with IGF-binding proteins. Iodine-125 14-18 insulin-like growth factor 1 Rattus norvegicus 58-63 6257337-11 1980 In contrast ILAs and IGF-1 and IGF-2 inhibited 125I-labeled insulin binding to its receptors in a dose-dependent fashion. Iodine-125 47-51 insulin-like growth factor 1 Rattus norvegicus 21-26 2948816-3 1987 Binding of 125I-labeled IGF-I (biosynthetic Thr59-IGF-I) to FRTL-5 was a function of time, temperature, and pH and was completely inhibited by high concentrations of unlabeled IGF-I. Iodine-125 11-15 insulin-like growth factor 1 Rattus norvegicus 24-29 2948816-3 1987 Binding of 125I-labeled IGF-I (biosynthetic Thr59-IGF-I) to FRTL-5 was a function of time, temperature, and pH and was completely inhibited by high concentrations of unlabeled IGF-I. Iodine-125 11-15 insulin-like growth factor 1 Rattus norvegicus 44-55 2948816-3 1987 Binding of 125I-labeled IGF-I (biosynthetic Thr59-IGF-I) to FRTL-5 was a function of time, temperature, and pH and was completely inhibited by high concentrations of unlabeled IGF-I. Iodine-125 11-15 insulin-like growth factor 1 Rattus norvegicus 50-55 6159199-4 1980 With each 125I-labeled peptide, significant inhibition of binding and parallel dose-response curves were observed with unlabeled IGF-I, IGF-II, and MSA. Iodine-125 10-14 insulin-like growth factor 1 Rattus norvegicus 129-134 2174008-4 1990 The binding of 125I-labeled IGF-I to crude membranes was measured in the same tissues. Iodine-125 15-19 insulin-like growth factor 1 Rattus norvegicus 28-33 2966061-1 1988 High affinity binding sites for 125I-labeled [Thr59]insulin-like growth factor I (IGF-I) were measured in rat median eminence by in vitro autoradiography with slide-mounted sections of frozen rat brain. Iodine-125 32-36 insulin-like growth factor 1 Rattus norvegicus 52-80 2966061-1 1988 High affinity binding sites for 125I-labeled [Thr59]insulin-like growth factor I (IGF-I) were measured in rat median eminence by in vitro autoradiography with slide-mounted sections of frozen rat brain. Iodine-125 32-36 insulin-like growth factor 1 Rattus norvegicus 82-87 2966061-8 1988 Binding of 125I-labeled [Thr59]IGF-I in the median eminence was significantly increased in the food-restricted rats, primarily due to an increase in the concentration of iodo-[Thr59]IGF-I-binding sites in the median eminence; the affinity (Kd) of binding was unchanged. Iodine-125 11-15 insulin-like growth factor 1 Rattus norvegicus 31-36 2966061-8 1988 Binding of 125I-labeled [Thr59]IGF-I in the median eminence was significantly increased in the food-restricted rats, primarily due to an increase in the concentration of iodo-[Thr59]IGF-I-binding sites in the median eminence; the affinity (Kd) of binding was unchanged. Iodine-125 11-15 insulin-like growth factor 1 Rattus norvegicus 182-187 3012553-6 1986 Affinity labeling with 125I-labeled MSA revealed that these atypical receptors had the same binding subunit (Mr 140,000) as classical insulin and IGF-I receptors. Iodine-125 23-27 insulin-like growth factor 1 Rattus norvegicus 146-151 221310-1 1979 Somatomedin in rat serum has been measured by a sensitive radioreceptor assay using 125I-labelled human somatomedin and human placental membrane. Iodine-125 84-88 insulin-like growth factor 1 Rattus norvegicus 0-11 221310-1 1979 Somatomedin in rat serum has been measured by a sensitive radioreceptor assay using 125I-labelled human somatomedin and human placental membrane. Iodine-125 84-88 insulin-like growth factor 1 Rattus norvegicus 104-115 16045806-4 2005 METHODS: Under barbiturate anesthesia, 125I-labeled insulin-like growth factor-1 (IGF-1) was injected into one lateral ventricle of normal Sprague-Dawley rats. Iodine-125 39-43 insulin-like growth factor 1 Rattus norvegicus 52-80 16045806-4 2005 METHODS: Under barbiturate anesthesia, 125I-labeled insulin-like growth factor-1 (IGF-1) was injected into one lateral ventricle of normal Sprague-Dawley rats. Iodine-125 39-43 insulin-like growth factor 1 Rattus norvegicus 82-87