PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6186008-2 1982 Human synthetic monomer CT was used for 125I-labelling and for preparation of standard sera. Iodine-125 40-44 calcitonin related polypeptide alpha Homo sapiens 24-26 2578663-1 1985 Binding sites for synthetic human 125I-labeled calcitonin gene-related peptide (125I-CGRP) have been demonstrated in membranes of the human nervous system. Iodine-125 34-38 calcitonin related polypeptide alpha Homo sapiens 85-89 6950419-3 1981 Specific CT binding measured with 125I-labeled salmon CT was highest in homogenates of the posterior hypothalamus and the median eminence, shown to contain the highest concentrations of endogenous CT in the brain; CT binding was less than 12% of hypothalamic binding in all of the other regions of the brain examined and was negligible in the pituitary. Iodine-125 34-38 calcitonin related polypeptide alpha Homo sapiens 9-11 6950419-3 1981 Specific CT binding measured with 125I-labeled salmon CT was highest in homogenates of the posterior hypothalamus and the median eminence, shown to contain the highest concentrations of endogenous CT in the brain; CT binding was less than 12% of hypothalamic binding in all of the other regions of the brain examined and was negligible in the pituitary. Iodine-125 34-38 calcitonin related polypeptide alpha Homo sapiens 54-56 6950419-3 1981 Specific CT binding measured with 125I-labeled salmon CT was highest in homogenates of the posterior hypothalamus and the median eminence, shown to contain the highest concentrations of endogenous CT in the brain; CT binding was less than 12% of hypothalamic binding in all of the other regions of the brain examined and was negligible in the pituitary. Iodine-125 34-38 calcitonin related polypeptide alpha Homo sapiens 54-56 6950419-3 1981 Specific CT binding measured with 125I-labeled salmon CT was highest in homogenates of the posterior hypothalamus and the median eminence, shown to contain the highest concentrations of endogenous CT in the brain; CT binding was less than 12% of hypothalamic binding in all of the other regions of the brain examined and was negligible in the pituitary. Iodine-125 34-38 calcitonin related polypeptide alpha Homo sapiens 54-56 16014619-6 2005 Direct saturation binding for 125I-labeled CGRP to HUVS cells and Scatchard analysis indicate specificity of the receptors for CGRP [dissociation constant (K(D)) = 67 nM, maximum binding capcity (Bmax) = 2.7 pmol/million cells]. Iodine-125 30-34 calcitonin related polypeptide alpha Homo sapiens 43-47 7316992-2 1981 Suspended cells of both lines specifically bound 125I-labelled salmon calcitonin with mean dissociation constants of 1.7 nM (MCF 7) and 1.4 nM (T 47D); mean receptor numbers were 5300 and 24400 per cell respectively. Iodine-125 49-53 calcitonin related polypeptide alpha Homo sapiens 70-80 16014619-6 2005 Direct saturation binding for 125I-labeled CGRP to HUVS cells and Scatchard analysis indicate specificity of the receptors for CGRP [dissociation constant (K(D)) = 67 nM, maximum binding capcity (Bmax) = 2.7 pmol/million cells]. Iodine-125 30-34 calcitonin related polypeptide alpha Homo sapiens 127-131 8701028-6 1996 Salmon CT inhibited the binding of 125I-labelled CGRP to branchial membranes with a lesser efficiency than that of the unlabelled hormone. Iodine-125 35-39 calcitonin related polypeptide alpha Homo sapiens 49-53 8701028-7 1996 A 40% inhibition of the 125I-labelled CGRP binding was observed in the presence of 2.6 and 26 nM CGRP and salmon CT, respectively. Iodine-125 24-28 calcitonin related polypeptide alpha Homo sapiens 38-42 8701028-7 1996 A 40% inhibition of the 125I-labelled CGRP binding was observed in the presence of 2.6 and 26 nM CGRP and salmon CT, respectively. Iodine-125 24-28 calcitonin related polypeptide alpha Homo sapiens 97-101 1313594-8 1992 In addition, 125I-labeled human calcitonin was specifically bound to KATO III cell membranes, and this binding was dose-dependently displaced by unlabeled calcitonin but not CGRP. Iodine-125 13-17 calcitonin related polypeptide alpha Homo sapiens 32-42 1313594-8 1992 In addition, 125I-labeled human calcitonin was specifically bound to KATO III cell membranes, and this binding was dose-dependently displaced by unlabeled calcitonin but not CGRP. Iodine-125 13-17 calcitonin related polypeptide alpha Homo sapiens 155-165 2247835-7 1990 CGRP was extracted and assayed by radioimmunoassay for iodine 125-labeled human CGRP. Iodine-125 55-65 calcitonin related polypeptide alpha Homo sapiens 0-4 1649597-2 1991 Rat liver plasma membranes contain a specific saturable binding site for 125I-labelled human CGRP-1. Iodine-125 73-77 calcitonin related polypeptide alpha Homo sapiens 93-99 1649597-7 1991 Specific binding of 125I-labelled human CGRP-1 to both liver and skeletal muscle membranes was inhibited by human CGRP-1 [IC50 (concn. Iodine-125 20-24 calcitonin related polypeptide alpha Homo sapiens 40-46 1649597-7 1991 Specific binding of 125I-labelled human CGRP-1 to both liver and skeletal muscle membranes was inhibited by human CGRP-1 [IC50 (concn. Iodine-125 20-24 calcitonin related polypeptide alpha Homo sapiens 114-120 2247835-7 1990 CGRP was extracted and assayed by radioimmunoassay for iodine 125-labeled human CGRP. Iodine-125 55-65 calcitonin related polypeptide alpha Homo sapiens 80-84 2159144-3 1990 125I-labeled CGRP was shown to bind to HUVECs and this binding was displaced by addition of unlabeled CGRP, suggesting the existence of specific CGRP receptors. Iodine-125 0-4 calcitonin related polypeptide alpha Homo sapiens 13-17 2159144-3 1990 125I-labeled CGRP was shown to bind to HUVECs and this binding was displaced by addition of unlabeled CGRP, suggesting the existence of specific CGRP receptors. Iodine-125 0-4 calcitonin related polypeptide alpha Homo sapiens 102-106 2159144-3 1990 125I-labeled CGRP was shown to bind to HUVECs and this binding was displaced by addition of unlabeled CGRP, suggesting the existence of specific CGRP receptors. Iodine-125 0-4 calcitonin related polypeptide alpha Homo sapiens 102-106