PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12007790-3 2002 NIH 3T3 cells expressing a hydroxytamoxifen-inducible oncogenic c-Raf-1-oestrogen receptor fusion protein (c-Raf-1-BxB-ER, N-BxB-ER cells) undergo morphological transformation upon stimulation of the Raf kinase. hydroxytamoxifen 27-43 v-raf-leukemia viral oncogene 1 Mus musculus 64-69 12007790-3 2002 NIH 3T3 cells expressing a hydroxytamoxifen-inducible oncogenic c-Raf-1-oestrogen receptor fusion protein (c-Raf-1-BxB-ER, N-BxB-ER cells) undergo morphological transformation upon stimulation of the Raf kinase. hydroxytamoxifen 27-43 v-raf-leukemia viral oncogene 1 Mus musculus 107-112 9464539-4 1998 Fusion of the c-Raf-1 kinase domain with the hormone binding domain of the estrogen receptor (c-Raf-1-BxB-ER) provides a 4-hydroxytamoxifen regulated form of the oncogenic c-Raf-1 kinase. hydroxytamoxifen 121-139 v-raf-leukemia viral oncogene 1 Mus musculus 14-19 9563474-1 1998 The selection of NIH 3T3 cells expressing a hydroxytamoxifen-inducible c-Raf-1-estrogen receptor fusion protein (c-Raf-1-BxB-ER) in the absence or presence of the inducer results in dramatic differences in the expression levels of the fusion protein. hydroxytamoxifen 44-60 v-raf-leukemia viral oncogene 1 Mus musculus 71-76 9563474-1 1998 The selection of NIH 3T3 cells expressing a hydroxytamoxifen-inducible c-Raf-1-estrogen receptor fusion protein (c-Raf-1-BxB-ER) in the absence or presence of the inducer results in dramatic differences in the expression levels of the fusion protein. hydroxytamoxifen 44-60 v-raf-leukemia viral oncogene 1 Mus musculus 113-118 9563474-2 1998 Hydroxytamoxifen-mediated constitutive activation of the Raf signal favors the selection of cells expressing low levels of c-Raf-1-BxB-ER. hydroxytamoxifen 0-16 v-raf-leukemia viral oncogene 1 Mus musculus 123-128 9464539-4 1998 Fusion of the c-Raf-1 kinase domain with the hormone binding domain of the estrogen receptor (c-Raf-1-BxB-ER) provides a 4-hydroxytamoxifen regulated form of the oncogenic c-Raf-1 kinase. hydroxytamoxifen 121-139 v-raf-leukemia viral oncogene 1 Mus musculus 94-99 9464539-4 1998 Fusion of the c-Raf-1 kinase domain with the hormone binding domain of the estrogen receptor (c-Raf-1-BxB-ER) provides a 4-hydroxytamoxifen regulated form of the oncogenic c-Raf-1 kinase. hydroxytamoxifen 121-139 v-raf-leukemia viral oncogene 1 Mus musculus 94-99 9464539-6 1998 4-hydroxytamoxifen mediated activation of the fusion protein in serum starved N-BxB-ER induces the expression of the c-myc gene within 2-6 h. Deletion of the c-Raf-1 kinase domain generates a mutant c-Raf-1 protein (c-Raf-1-C4B), which can directly interact with the effector domain of the Ras protein and thereby block Ras mediated signalling. hydroxytamoxifen 0-18 v-raf-leukemia viral oncogene 1 Mus musculus 158-163 9464539-6 1998 4-hydroxytamoxifen mediated activation of the fusion protein in serum starved N-BxB-ER induces the expression of the c-myc gene within 2-6 h. Deletion of the c-Raf-1 kinase domain generates a mutant c-Raf-1 protein (c-Raf-1-C4B), which can directly interact with the effector domain of the Ras protein and thereby block Ras mediated signalling. hydroxytamoxifen 0-18 v-raf-leukemia viral oncogene 1 Mus musculus 199-204 9464539-6 1998 4-hydroxytamoxifen mediated activation of the fusion protein in serum starved N-BxB-ER induces the expression of the c-myc gene within 2-6 h. Deletion of the c-Raf-1 kinase domain generates a mutant c-Raf-1 protein (c-Raf-1-C4B), which can directly interact with the effector domain of the Ras protein and thereby block Ras mediated signalling. hydroxytamoxifen 0-18 v-raf-leukemia viral oncogene 1 Mus musculus 199-204