PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14617793-2 2003 Although the cytotoxic taxanes paclitaxel and docetaxel are substrates for Pgp-mediated efflux, the semisynthetic taxane analogue ortataxel inhibits drug efflux mediated by Pgp as well as, as we recently demonstrated, MRP-1 and BCRP. IDN 5109 130-139 ATP binding cassette subfamily C member 1 Homo sapiens 218-223 15060738-6 2004 RESULTS: Ortataxel effectively modulated drug retention and cytotoxicity in cell lines overexpressing MRP-1 and BCRP(R482), in addition to Pgp. IDN 5109 9-18 ATP binding cassette subfamily C member 1 Homo sapiens 102-107