PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18494000-4	2008	Moreover, inhibitors of caspase-3, -8 and -9 (Ac-DEVD-CHO, Z-IETD-FMK and Z-LEHD-FMK) efficiently blocked emodin-induced apoptosis in TNF-alpha treated HASMC.	acetyl-aspartyl-glutamyl-valyl-aspartal	46-57	tumor necrosis factor	Homo sapiens	134-143	
10209503-10	1999	Moreover, peptide inhibitor for caspase II subfamily, Ac-DEVD-CHO, reduced the cytolysis of TNF-alpha-treated cholangiocarcinoma cells.	acetyl-aspartyl-glutamyl-valyl-aspartal	54-65	tumor necrosis factor	Homo sapiens	92-101	
11414450-7	2000	The cleavage of PARP was inhibited when the cell line was pretreated with peptide inhibitor, Ac-DEVD-CHO, suggesting that apoptosis induced by TNF-alpha of this cell line involves activation of caspase II subfamily.	acetyl-aspartyl-glutamyl-valyl-aspartal	93-104	tumor necrosis factor	Homo sapiens	143-152	
10088775-12	1999	More importantly, Z-IETD-FMK, a caspase 8 inhibitor, and Ac-DEVD-CHO, a caspase 3 inhibitor, almost completely inhibited Fas-mediated apoptosis of TNFalpha-treated cultured OA synoviocytes, whereas Ac-YVAD-CHO, a caspase 1 inhibitor, did not.	acetyl-aspartyl-glutamyl-valyl-aspartal	57-68	tumor necrosis factor	Homo sapiens	147-155	
9144192-3	1997	Inhibition of caspases by expression of a cowpox virus-derived inhibitor, CrmA, or by a specific tetrapeptide inhibitor of CPP32/caspase-3, acetyl-Asp-Glu-Val-Asp-aldehyde (Ac-DEVD-CHO), inhibited TNF-induced activation of cPLA2 and apoptosis.	acetyl-aspartyl-glutamyl-valyl-aspartal	140-171	tumor necrosis factor	Homo sapiens	197-200