PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17594508-6	2007	In contrast, a well-known caspase-3 inhibitor, Ac-DEVD-CHO, inhibits all these caspases with similar Kiapp values.	acetyl-aspartyl-glutamyl-valyl-aspartal	47-58	caspase 8	Homo sapiens	79-87	
19084044-12	2009	Our experiments with caspase inhibitors Ac-DEVD-CHO, Z-IETD-FMK and Z-VAD-FMK inhibited capsase-3, 8 cleavages but did not prevent OA-induced apoptosis and DNA fragmentation.	acetyl-aspartyl-glutamyl-valyl-aspartal	40-51	caspase 8	Homo sapiens	21-28	
29223591-5	2018	Western blot and immunofluorescence staining were conducted to analyze the effects of MH and Ac-DEVD-CHO on the expressions of caspase-3, caspase-8, and PARP.	acetyl-aspartyl-glutamyl-valyl-aspartal	93-104	caspase 8	Homo sapiens	138-147	
16754997-5	2006	The caspases, caspase-9 and -3, but not caspase-8, were found to be activated in response to RPAE treatment, and the caspase-3 inhibitor, Ac-DEVD-CHO, and the caspase-9 inhibitor, z-LEHD-FMK, but not the caspase-8 inhibitor, z-IETD-FMK, attenuated RPAE-induced DNA fragmentation and PARP cleavage.	acetyl-aspartyl-glutamyl-valyl-aspartal	138-149	caspase 8	Homo sapiens	4-12	
11210827-6	2000	A broad-spectrum caspase inhibitor, z-VAD-fmk, completely prevented all apoptotic changes, except for the depletion of delta psi m. Both Ac-DEVD-CHO and Ac-IETD-CHO, inhibitors of caspase -3 and -8, respectively, effectively inhibited typical chromatin condensation to almost the same extent.	acetyl-aspartyl-glutamyl-valyl-aspartal	137-148	caspase 8	Homo sapiens	17-24	
10358093-7	1999	Both NO and the caspase inhibitor, Ac-DEVD-CHO, prevented the appearance of the four newly labeled spots or active caspases.	acetyl-aspartyl-glutamyl-valyl-aspartal	35-46	caspase 8	Homo sapiens	115-123	
29223591-8	2018	We found that MH (32  C) and Ac-DEVD-CHO (5.96 muMol/L) had equal effects on blocking the activation of caspase-3 and the OGD-induced cleavage of PARP, but neither had any effect on the activation of caspase-8, which goes on to activate caspase-3 in the apoptotic pathway.	acetyl-aspartyl-glutamyl-valyl-aspartal	29-40	caspase 8	Homo sapiens	200-209	
21229646-6	2010	RESULTS: cell death rate induced by the tested compound was decreased with the caspase-3 inhibitor Ac-DEVD-CHO, and the inhibitors of caspase-2 (Z-VDVAD-FMK) and -4 (ZYVAD- FMK), but not with the caspase-9 inhibitor z-LEHD-FMK and caspase-8 inhibitor z-IETD-FMK.	acetyl-aspartyl-glutamyl-valyl-aspartal	99-110	caspase 8	Homo sapiens	231-240	
24039967-6	2013	Moreover, caspase-8 and caspase-3 activation and PARP-1 cleavage were strongly inhibited/blocked by the addition of the specific caspase inhibitors Z-VAD-FMK and Ac-DEVD-CHO.	acetyl-aspartyl-glutamyl-valyl-aspartal	162-173	caspase 8	Homo sapiens	10-19