PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16277530-12	2005	As the key difference between LPO (and other mammalian peroxidases) and HRP is the presence of two covalent ester links between the heme and the protein, we propose that these links contribute to steric protection of the adjacent heme vinyl groups.	Esters	108-113	lactoperoxidase	Homo sapiens	30-33	
16651262-3	2006	This reaction is not observed with lactoperoxidase (LPO), in which the heme is covalently bound to the protein via two ester bonds between carboxylic side chains and heme methyl groups.	Esters	119-124	lactoperoxidase	Homo sapiens	35-50	
16651262-3	2006	This reaction is not observed with lactoperoxidase (LPO), in which the heme is covalently bound to the protein via two ester bonds between carboxylic side chains and heme methyl groups.	Esters	119-124	lactoperoxidase	Homo sapiens	52-55	
8631940-15	1996	From this work and literature analysis, we suggest that the non-extractable "heme l" of LPO has the two vinyl groups of heme b but lacks the 2-sulfonium-vinyl linkage of heme m. The observed red shifts in LPO spectra may derive from ester linkages to protein as for MPO.	Esters	233-238	lactoperoxidase	Homo sapiens	88-91	
10358043-12	1999	From a parallel study with LPO, we show that Asp-125 and Glu-275 are engaged in ester linkage.	Esters	80-85	lactoperoxidase	Homo sapiens	27-30	
8631940-15	1996	From this work and literature analysis, we suggest that the non-extractable "heme l" of LPO has the two vinyl groups of heme b but lacks the 2-sulfonium-vinyl linkage of heme m. The observed red shifts in LPO spectra may derive from ester linkages to protein as for MPO.	Esters	233-238	lactoperoxidase	Homo sapiens	205-208	
33882424-2	2021	The prosthetic heme group is covalently attached to LPO through two ester linkages involving conserved glutamate and aspartate residues.	Esters	68-73	lactoperoxidase	Homo sapiens	52-55	
33389415-5	2021	The heme prosthetic group is covalently linked in LPO through two ester bonds involving conserved residues Glu258 and Asp108.	Esters	66-71	lactoperoxidase	Homo sapiens	50-53	
28762722-3	2017	Recently, we reported the occurrence of stable LPO-like counterparts with two heme to protein ester linkages in bacteria.	Esters	94-99	lactoperoxidase	Homo sapiens	47-50