PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10910056-0	2000	Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene.	anthracene	129-139	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	0-18	
10910056-4	2000	This investigation demonstrates that CYP1B1 null mice are almost completely protected from the acute bone marrow cytotoxic and preleukemic effects of the prototypic PAH 7,12-dimethylbenz[a]anthracene (DMBA).	anthracene	189-199	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	37-43	
10051580-0	1999	Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas.	anthracene	73-83	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	16-22	
10570060-1	1999	We previously demonstrated that murine bone marrow stromal cells express high levels of cytochrome P4501B1 (CYP1B1) that metabolizes 7,12-dimethylbenza[a]anthracene (DMBA), and that DMBA activates the Ah receptor (AhR) in these cells in vitro.	anthracene	154-164	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	88-106	
10570060-1	1999	We previously demonstrated that murine bone marrow stromal cells express high levels of cytochrome P4501B1 (CYP1B1) that metabolizes 7,12-dimethylbenza[a]anthracene (DMBA), and that DMBA activates the Ah receptor (AhR) in these cells in vitro.	anthracene	154-164	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	108-114	
8033136-4	1994	Cells treated with medium conditioned by several days of cell growth supported increases in the dimethylbenz(a)anthracene induction of mRNA expression of a new mouse cytochrome P450 gene designated Cyp1b1, aryl hydrocarbon hydroxylase activity, cytotoxicity, and the frequency of neoplastic transformation.	anthracene	111-121	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	198-204	
12584151-0	2003	CYP1A1 and CYP1B1 in blood-brain interfaces: CYP1A1-dependent bioactivation of 7,12-dimethylbenz(a)anthracene in endothelial cells.	anthracene	99-109	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	11-17	
17365149-0	2007	Differential effect of 7,12-dimethylbenz[a]anthracene on human and mouse CYP1B1 from livers of castrated transgenic mice.	anthracene	43-53	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	73-79	
15580705-2	2004	We have shown previously that mice deficient in CYP1B1 were resistant to induced tumors after 7,12-dimethylbenz[a]anthracene exposure.	anthracene	114-124	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	48-54	
14613719-1	2003	We have previously used CYP1B1-null mice to demonstrate that dimethylbenz(a)anthracene (DMBA) requires CYP1B1 for bone marrow (BM) toxicity.	anthracene	76-86	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	24-30	
14613719-1	2003	We have previously used CYP1B1-null mice to demonstrate that dimethylbenz(a)anthracene (DMBA) requires CYP1B1 for bone marrow (BM) toxicity.	anthracene	76-86	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	103-109	
12584151-1	2003	Immunohistochemistry and autoradiography were used to identify sites of the cytochrome P450 enzymes (P450) 1A1 and 1B1 expression and activation of 7,12-dimethylbenz(a)anthracene (DMBA), in the brain of rodents pretreated with the aryl hydrocarbon receptor (AhR) agonists beta-naphthoflavone (BNF), 3,3",4,4",5-pentachlorobiphenyl or vehicle.	anthracene	168-178	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	76-118	
12584184-0	2003	CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity.	anthracene	69-79	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	0-6	
12584184-0	2003	CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity.	anthracene	69-79	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	128-134	
12584184-1	2003	We showed previously that CYP1B1-null mice developed 10 times less lymphomas than wild-type mice after receiving 7,12-dimethylbenz[a]anthracene (DMBA).	anthracene	133-143	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	26-32