PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11792688-7	2002	The corresponding values for 1"-hydroxymidazolam formation (CYP3A) were 3.7, 6.1, 11.7, and 15.2 microl/min/mg, respectively.	1-hydroxymethylmidazolam	29-48	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	60-65	
20448858-2	2010	1"-Hydroxy midazolam and midazolam 1-hydroxylation catalyzed by CYP3A were analyzed by high performance liquid chromatography (HPLC).	1-hydroxymethylmidazolam	0-20	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	64-69	
34388602-1	2021	Midazolam (MDZ) is a short-acting benzodiazepine with rapid onset of action, which is metabolized by CYP3A isoenzymes to two hydroxylated metabolites, 1"-hydroxymidazolam and 4-hydroxymidazolam.	1-hydroxymethylmidazolam	151-170	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	101-106	
25953268-5	2015	According to the ex vivo experiment, the activity of CYP3A was measured by the quantification of 1-hydroxymidazolam, which was the metabolite from CYP3A probe substrate, midazolam.	1-hydroxymethylmidazolam	97-115	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	53-58	
25953268-5	2015	According to the ex vivo experiment, the activity of CYP3A was measured by the quantification of 1-hydroxymidazolam, which was the metabolite from CYP3A probe substrate, midazolam.	1-hydroxymethylmidazolam	97-115	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	147-152	
24329500-5	2014	Hepatic clearance of docetaxel was enhanced in vitro and in vivo at dosage of 120 and 180 mg kg(-1), and CYP3A activity was up-regulated by measuring the formation rate of 1-hydroxymidazolam.	1-hydroxymethylmidazolam	172-190	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	105-110	
24486211-10	2014	Pretreatment with GL notably increased the AUC  of 1 -hydroxymidazolam (OH-MDZ) and the ratio of AUC  of OH-MDZ to MDZ, demonstrating induction of the activity of CYP3A by GL.	1-hydroxymethylmidazolam	51-70	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	163-168