PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32058824-8 2020 Additionally, we found interfering Beclin-1using Beclin-1-shRNA also enhanced the proliferation-inhibiting and apoptosis-inducing effects of DDP on gastric cancer cells by inhibiting phosphorylation of Akt. 2-dimethylaminoethyl(dimethylamido)phosphonofluoridate 141-144 AKT serine/threonine kinase 1 Homo sapiens 202-205 31612051-0 2019 Polyphyllin I and VII potentiate the chemosensitivity of A549/DDP cells to cisplatin by enhancing apoptosis, reversing EMT and suppressing the CIP2A/AKT/mTOR signaling axis. 2-dimethylaminoethyl(dimethylamido)phosphonofluoridate 62-65 AKT serine/threonine kinase 1 Homo sapiens 149-152 31612051-5 2019 CIP2A and its downstream protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway also plays a role in mediating DDP resistance. 2-dimethylaminoethyl(dimethylamido)phosphonofluoridate 124-127 AKT serine/threonine kinase 1 Homo sapiens 43-46 31612051-10 2019 Furthermore, PPI and PPVII reversed the EMT and suppressed CIP2A and its downstream AKT/mTOR signaling cascade in A549/DDP cells. 2-dimethylaminoethyl(dimethylamido)phosphonofluoridate 119-122 AKT serine/threonine kinase 1 Homo sapiens 84-87