PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31957833-4 2020 Our study aimed to investigate the effects of long non-coding RNA (lncRNA) KCNQ1 overlapping transcript 1 (KCNQ1OT1) on DDP resistance of tongue cancer and the underlying mechanism. 2-dimethylaminoethyl(dimethylamido)phosphonofluoridate 120-123 KCNQ1 opposite strand/antisense transcript 1 Homo sapiens 75-105 31957833-4 2020 Our study aimed to investigate the effects of long non-coding RNA (lncRNA) KCNQ1 overlapping transcript 1 (KCNQ1OT1) on DDP resistance of tongue cancer and the underlying mechanism. 2-dimethylaminoethyl(dimethylamido)phosphonofluoridate 120-123 KCNQ1 opposite strand/antisense transcript 1 Homo sapiens 107-115 31957833-13 2020 Animal experiment revealed the effect of KCNQ1OT1 on DDP resistance of tongue cancer cells in vivo. 2-dimethylaminoethyl(dimethylamido)phosphonofluoridate 53-56 KCNQ1 opposite strand/antisense transcript 1 Homo sapiens 41-49 31957833-14 2020 RESULTS: KCNQ1OT1 was upregulated in DDP-resistant tongue cancer tissues and cells, and mainly expressed in cytoplasm. 2-dimethylaminoethyl(dimethylamido)phosphonofluoridate 37-40 KCNQ1 opposite strand/antisense transcript 1 Homo sapiens 9-17 31957833-15 2020 Functionally, the knockdown of KCNQ1OT1 inhibited the survival rate, proliferation, migration, invasion, and EMT of the DDP-resistant tongue cancer cells. 2-dimethylaminoethyl(dimethylamido)phosphonofluoridate 120-123 KCNQ1 opposite strand/antisense transcript 1 Homo sapiens 31-39 31957833-19 2020 Furthermore, KCNQ1OT1 knockdown reduced the DDP-resistant tumor growth and weight through the miR-124-3p/TRIM14 axis in vivo. 2-dimethylaminoethyl(dimethylamido)phosphonofluoridate 44-47 KCNQ1 opposite strand/antisense transcript 1 Homo sapiens 13-21 31957833-20 2020 CONCLUSIONS: LncRNA KCNQ1OT1 promotes the DDP resistance of tongue cancer by sponging miR-124-3p to regulate TRIM14 expression. 2-dimethylaminoethyl(dimethylamido)phosphonofluoridate 42-45 KCNQ1 opposite strand/antisense transcript 1 Homo sapiens 20-28